Fox-Fordyce Disease in Two Prepubertal Girls: Histopathologic Demonstration of Eccrine Sweat Gland Involvement

Vulva and Vagina

“…184 Improvement may also be observed during pregnancy or with the use of oral contraceptives. Rarely, prepubertal girls may be affected.…”

Fox-Fordyce-Krankheit

“…In sehr seltenen Fällen konnten Porokarzinome im Genitalbereich und periungual nachgewiesen werden [6,10,13]. In sehr seltenen Fällen konnten Porokarzinome im Genitalbereich und periungual nachgewiesen werden [6,10,13].…”

Fox-Fordyce Disease in Daughter and Father

“…Pruritus is thought to be caused by extravasation of sweat [2] . The exact pathogenesis of the disease remains unknown although emotional factors, hormonal influences and chemical changes in the sweat components are all thought to be contributors [5] .…”