FR - ¿Existe una resistencia real al tratamiento de la escabiosis con permetrina?

Velasco-Amador, JP.; Prados-Carmona, Alvaro; Ruiz‐Villaverde, Ricardo

doi:10.1016/j.ad.2022.05.036

Cited by 1 publication

(1 citation statement)

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“…The main reason could be treatment failure, which has generally been attributed to various causes, such as incorrect application of the cream by patients, failure to simultaneously treat cohabitants, or insufficient disinfection of the environment [ 26 , 27 , 28 ]. However, an increasing number of dermatologists are suggesting a real resistance to permethrin after ruling out the previously described errors and achieving a cure with other active principles for topical use, including magistral preparations, such as sulfur in an ointment base (petrolatum) or benzyl benzoate [ 29 ]. For example, Sunderkötter et al warned in 2018 of a surprising increase in the incidence of scabies in Germany and described, among the possible causes, the development of resistance to permethrin [ 30 ].…”

Section: Resultsmentioning

confidence: 99%

Study of the Use of Permethrin 5% Cream in Galicia (Spain) between 2018 and 2021

Vázquez-Prieto

Liste

Paniagua

2023

Infectious Disease Reports

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Drug utilization studies can provide direct insights into how a drug is used in real-world conditions and can give a rough estimate of the proportion of the study population treated with it. In the present work, we examined the consumption of permethrin 5% cream in the four provinces of Galicia (a Spanish autonomous community) and described the seasonal variability and the annual evolution of its consumption between 2018 and 2021. A descriptive, cross-sectional, and retrospective study of the consumption of this drug, expressed in defined daily dose per 1000 inhabitants per day (DID), was carried out. The results obtained revealed differences between the amounts consumed in the four Galician provinces (p < 0.001). No specific geographical pattern was observed; however, the results suggested a marked seasonality and a slightly increasing global trend in the consumption of permethrin 5% cream throughout the study period. Since the only authorized indication of this drug in the study area is the treatment of scabies, this work may give an idea of the epidemiological situation of the disease in Galicia and serve to establish public health strategies against this parasitosis.

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