Fractalkine as a severity marker of atopic dermatitis in infants and toddlers

Abstract

Introduction: Atopic dermatitis (AD) is a common chronic inflammatory skin disease. The aim of the study were the relationship determining between level of serum fractalkine and clinical signs of AD; and establishing correlation between the level of serum fractalkine and paraclinical signs of AD (total Ig E level, immunogram value). Material and methods: 60 children with clinical manifestations of AD in the exacerbation period of the disease (main group) and 16 healthy children without chronic diseases (control group) took part in the clinical study. Results: The study showed that the serum fractalkine level is elevated in all forms of AD severity: mild -8.55