SUMMARYIn this paper the authors introduce a hierarchic fractal model to describe bone hereditariness. Indeed, experimental data of stress relaxation or creep functions obtained by compressive/tensile tests have been proved to be fit by power-law with real exponent 0 1. The rheological behavior of the material has therefore been obtained, using the Boltzmann-Volterra superposition principle, in terms of real order integrals and derivatives (fractional-order calculus). It is shown that the power-laws describing creep/relaxation of bone tissue may be obtained introducing a fractal description of bone cross-section and the Hausdorff dimension of the fractal geometry is then related to the exponent of the power-law. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59
INTRODUCTIONMathematical models of material behavior are fundamental for optimization and for reliable design of engineered devices. Furthermore, the key issue is to be able to track down the multiscale behavior from the nano-to the macrolevel, with particular regard to biological and bioinspired materials.Indeed, the mechanical interactions among biomedical devices and biological tissues play a keyrole for the optimization of physiological functionality of such devices owing to the reduction of immunologic response. In this regard, it is clear that the detailed knowledge of the features of biological tissues at the different scales and their interactions with the devices is a crucial step to optimize the mechanical and physical response of the compound.Physical parameters of biological tissues usually investigated in scientific literature involve stiffness, strength, toughness, permeability, porosity, thermal conductivity among others [1,2,3].Besides these important features, mineralized bone tissues must provide load carrying capabilities and they exhibit a marked time-dependent behavior under applied loads. In this context, the term hereditariness is usually used in the sense that the actual response of bone material in terms of stress/displacement depends on previously applied stress/strain. This feature is macroscopically detectable by stress relaxation and creep observed in classical traction/compression mechanical tests. During a relaxation test, the imposed strain is held constant and a measure of the stress is monitored showing that it is a decreasing function of time; similarly, in a creep test an imposed constant stress is applied and a continuous monitoring of the strain is considered showing that it is an increasing function of time. Both these tests highlight the hereditariness feature of such material; the past undergone stress or strain history influence the future response of the specimen. A similar time-dependent behavior also arises in mineralized tissues as ligaments and tendons. Indeed the high stiffness (but highly brittleness) of the hydroxyapatite cryst...