Fractional Exhaled Nitric Oxide in Relation to Asthma, Allergic Rhinitis, and Atopic Dermatitis in Chinese Children

Abstract

Both asthma and AR could independently increase the FeNO levels in Chinese schoolchildren. Other diseases besides asthma should be considered when applying FeNO as a screening tool for asthma in Chinese children.

Sick building syndrome (SBS) among office workers in a Malaysian university — Associations with atopy, fractional exhaled nitric oxide (FeNO) and the office environment

“…We found only one study on SBS symptoms among office workers and FeNO levels and this study found no association between nasal symptoms and FeNO levels (Akpinar-Elci et al, 2008). However, two recent epidemiological studies among school children in China demonstrated that rhinitis is more common at higher FeNO levels (Xu et al, 2011;Zhao et al, 2013).…”

Association between fine particulate matter chemical constituents and airway inflammation: A panel study among healthy adults in China

“…Fractional exhaled nitric oxide (FeNO) is a well-established airway inflammatory biomarker employed in both clinical practice and epidemiological studies due to its high reproducible and noninvasive nature (Adamkiewicz et al, 2004;American Thoracic and European Respiratory, 2005;Dales et al, 2008;Dweik et al, 2011;Liu et al, 2009). A wide array of epidemiological studies has demonstrated a significant link between a short-term exposure to PM 2.5 and elevated FeNO levels (Chen et al, 2015b;Xu et al, 2011;Zhao et al, 2013). PM 2.5 is composed of a vast number of chemical constituents.…”

Respiratory symptoms and fractional exhaled nitric oxide (FeNO) among students in Penang, Malaysia in relation to signs of dampness at school and fungal DNA in school dust

“…Fraction of exhaled nitric oxide (FeNO) has recently been used in epidemiological studies in Asia (Xu et al, 2011;Zhao et al, 2013;Lim et al, 2015). FeNO is a biomarker of TH2 driven lower airway inflammation linked to allergic asthma (Alving and Malinovschi, 2010) rhinitis (Xu et al, 2011, Zhao et al, 2013Lim et al, 2015a) and sick building syndrome (SBS) symptoms (Lim et al, 2015b).…”

“…FeNO is a biomarker of TH2 driven lower airway inflammation linked to allergic asthma (Alving and Malinovschi, 2010) rhinitis (Xu et al, 2011, Zhao et al, 2013Lim et al, 2015a) and sick building syndrome (SBS) symptoms (Lim et al, 2015b). FeNO has been measured among office workers in Malaysia (Lim et al, 2015, Lim et al, 2016 but we found no previous publications from Malaysia, or any other tropical country, on associations between FeNO and the school environment.…”