2005
DOI: 10.1111/j.1532-5415.2005.53405.x
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Frailty: Emergence and Consequences in Women Aged 65 and Older in the Women's Health Initiative Observational Study

Abstract: These results support the robustness of the concept of frailty as a geriatric syndrome that predicts several poor outcomes in older women. Underweight, obesity, smoking, and depressive symptoms are strongly associated with the development of frailty and represent important targets for prevention.

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Cited by 894 publications
(444 citation statements)
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“…Previous studies that have established a link between frailty and fractures have utilized measures which categorize individuals into discrete categories (i.e., frail/pre-frail/nonfrail) [9][10][11][12]14]. In cohorts which utilized the frailty phenotype [5,9,12,14] or a simplified version [10,11], individuals classified as frail versus nonfrail had greater risk of incident hip and/or nonvertebral fractures.…”
Section: Discussionmentioning
confidence: 99%
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“…Previous studies that have established a link between frailty and fractures have utilized measures which categorize individuals into discrete categories (i.e., frail/pre-frail/nonfrail) [9][10][11][12]14]. In cohorts which utilized the frailty phenotype [5,9,12,14] or a simplified version [10,11], individuals classified as frail versus nonfrail had greater risk of incident hip and/or nonvertebral fractures.…”
Section: Discussionmentioning
confidence: 99%
“…In cohorts which utilized the frailty phenotype [5,9,12,14] or a simplified version [10,11], individuals classified as frail versus nonfrail had greater risk of incident hip and/or nonvertebral fractures. In contrast, a study which utilized a nine-item measure similar to the frailty phenotype did not find a significant association between frailty/nonfrailty status and fractures [15].…”
Section: Discussionmentioning
confidence: 99%
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“…The results of the Women Health Initiative, on the other hand, showed that women with HF suffered from frailty syndrome six-seven times more often than those without HF [19].…”
Section: Frailty Syndromementioning
confidence: 99%