Frailty in elderly patients with acute heart failure increases readmission

Umehara, Takuya; Kaneguchi, Akinori; Katayama, Nobuhisa; Kawakami, Wataru; Kuwahara, Daisuke; Kito, Nobuiro; Kakehashi, Masayuki

doi:10.1016/j.hrtlng.2022.08.021

Cited by 5 publications

(4 citation statements)

References 40 publications

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“…On the other hand, the odds of being in the always zero group decreased by 11.5% for a unit increase in body mass index (Coef. = 0.115: 95% CI: 0.0342, 0.196), 0.004, which is consistent with the ndings of previous studies in Japan [23], [24] and the US [25]. However, these ndings contradict those of studies in China [22,26] and Australia [19].…”

Section: Discussionsupporting

confidence: 88%

Number of readmissions and determinants among patients with heart failure at referral hospitals in the Amhara region, Northwest Ethiopia; 2023.

Gedfew,

Tesfaye,

Amha

et al. 2024

Preprint

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Aim: This study aimed to determine the number of readmissions among patients with heart failure and identify the determinants of heart failure among patients at referral hospitals in the Amhara region, North western Ethiopia, in 2023. Study design: A cross-sectional study design was employed using zero-inflated negative binomial models. Methods: Data were collected from patients with heart failure at referral hospitals in the Amhara region from September 2022 to February 2023. The data were collected from 663 patients with heart failure using chart reviews and interviewer-administered questions. Results: In this study, 237 (35.7%) patients with heart failure were readmitted at least once. The study showed that for every unit increase in the respiratory rate, the number of readmissions among patients with heart failure increased by 1.5% (IRR=.0.015; 95% CI=0.0004, 0.031), 0.044. In addition, as the duration of medication intake increased by one unit, the number of readmissions increased by 1.1% (IRR. =.0.011: 95% CI: 0.016, 0.051), 0.0001, while keeping all the other model variables constant. Similarly, compared with those of patients with good social support, the number of readmissions of patients with poor social support decreased by 59.4% (IRR=-1.595: 95% CI=-0.02, -0.005), 0.041. On the other hand, when thebody mass index increased by one unit, the odds of being in the always-zero group increased by 11.5% (IRR = 0.115: 95% CI: 0.035, 0.196), 0.004. Moreover, when the pulse rate increased by one unit, the odds of being in the always zero group decreased by 1.27% (IRR = -0.013: 95% CI: -0.025, -0.008), 0.036. Implications for Clinical Practice: Determining the factors that lead to heart failure (HF) readmission is essential for developing effective interventions to lower the number of readmissions and hospital stays that may negatively impact patients’ and their families' overall socioeconomic status. Additionally, this study provides a baseline for the progress of nursing research and education as well as input for policy makers, all of which will help to improve nursing practice. Patient or Public Contribution: Improves patients overall quality of care

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Section: Discussionsupporting

confidence: 88%

Number of readmissions and determinants among patients with heart failure at referral hospitals in the Amhara region, Northwest Ethiopia; 2023.

Gedfew,

Tesfaye,

Amha

et al. 2024

Preprint

View full text Add to dashboard Cite

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Section: Discussionmentioning

confidence: 99%

“…A retrospective study by Umehara et al 13 suggested that the high frailty severity and low LVEF might act synergistically to cause physical deterioration and an increase in readmissions among HF patients. 13 Advancing age was associated with frailty. 14 , 15 The underlying reason for the increasing prevalence of frailty with aging might be associated with degenerative disease and reduced reserve function of certain organs in the elderly.…”

Section: Discussionmentioning

confidence: 99%

Influence of Aging on Outcomes of Sacubitril/Valsartan in Hypertensive Patients with Heart Failure: A Multicenter Retrospective Study

Zuo

2024

Anatol J Cardiol

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Background: The aim of this study was to investigate the influence of aging on the effectiveness and tolerance of sacubitril/valsartan (sac/val) among hypertensive patients complicated with heart failure in a real-world setting. Methods: This multicenter, retrospective study included patients (≥18 years old) admitted with a diagnosis of hypertension and heart failure, starting sac/val therapy between January 2020 and December 2021 from 3 medical centers. Patients were grouped by the cutoff age of 65 years. Outcomes were collected 31-365 days after the initiation of sac/val and were compared in a matched cohort after 1 : 1 propensity score matching (PSM). Results: A total of 794 patients were finally analyzed. Blood pressure and cardiac functions improved significantly compared with values at baseline. There were 269 patients in each cohort (<65 years and ≥65 years) after PSM. After PSM, the incidence of hyperuricemia and hypotension in the elderly patients (≥65 years) was significantly higher than in those <65 years of age. Kaplan–Meier estimate suggested that the cumulative incidence of new or recurrent cardiovascular events increased significantly at the age of ≥65 years after the point of 3 months (log-rank P = .00087). Conclusion: Sac/val benefited patients in both cohorts by improving blood pressure and cardiac function. Elderly patients (≥65 years) were susceptible to hypotension, low diastolic blood pressure, hyperuricemia, and underwent cardiac-related readmissions more frequently.

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“…Hence, this has obvious subjectivity and variability. In recent studies, some clinical indicators such as brain natriuretic peptide (BNP) [ 15 ], left ventricular ejection fraction (LVEF) [ 16 ], and left atrial internal diameter at end-diastole (LAIDd) [ 17 ], was reported to be closely related to frailty. We suppose incorporating these clinical indicator variables may be more effective and available for frailty in older patients with HF.…”

Section: Introductionmentioning

confidence: 99%

Development and validation of dynamic nomogram of frailty risk for older patients hospitalized with heart failure

Chen

Qin

et al. 2023

International Journal of Nursing Sciences

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Frailty in elderly patients with acute heart failure increases readmission

Cited by 5 publications

References 40 publications

Number of readmissions and determinants among patients with heart failure at referral hospitals in the Amhara region, Northwest Ethiopia; 2023.

Number of readmissions and determinants among patients with heart failure at referral hospitals in the Amhara region, Northwest Ethiopia; 2023.

Influence of Aging on Outcomes of Sacubitril/Valsartan in Hypertensive Patients with Heart Failure: A Multicenter Retrospective Study

Development and validation of dynamic nomogram of frailty risk for older patients hospitalized with heart failure

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