Francis Peyton Rous

Kumar, Prasanna; Murphy, Frederick A.

doi:10.3201/eid1904.130049

Cited by 7 publications

(4 citation statements)

References 8 publications

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“…The HPV has been most important agent in developing cervical cancer the correlation between them was established by Dr. Hausen and Durst (1983). They identified it by isolating HPV of type 16 and 18 and several other high risk types of HPV (51,52,56,58,59) from the cervical scrap [30,31] also HPV and tar together was found to have induced squamous cell carcinoma as demonstrated by Peyton Rous in (1934). Tar is obtained from cigarette and smoke from burning wood.…”

Section: • Head Neckmentioning

confidence: 99%

A Review on Role of Human Papilloma Virus (HPV) in Health-Related Diseases

Singh¹,

Ahmad²,

Srivastava³

et al. 2020

AMDHS

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Human Papilloma Virus (HPV) is a DNA tumor virus with double stranded and non-enveloped DNA of 8 kilobase. Its genome is covered by capsid protein with icosahedral symmetry and a diameter of 55nm. It induces proliferative lesions in mucosal and cutaneous epithelia. It is ubiquitous in nature and have been detected in both animals and humans and well adapted to their host. More than 100 types of HPVs are present and they all are involved in causing infection in squamous epithelial cells of skin and mucosa, this eventually leads to papilloma's or warts benign type. The continuous infection with high risk HPV type causes cervical cancers and also anal cancer, vulvar, vaginal, penile and laryngeal papillomatosis. The HPV with cervical cancer association increase with elevation in number of squamous cell carcinoma at the sites of lesions in people. This infection is frequently noticed in a population with suppressed immune system. The HPV infects immature squamous epithelium at the squamocolumnal junction of cervix. The relation of HPV with non-melanoma skin cancer (NMSC) is clinically important as it is most common form of malignancy among fair skinned populations. This results in cytopathological changes induced by the virus which cytology and histology clearly diagnose as precancerous lesions which eventually result to become cancer. The HPV can be diagnosed by several techniques mainly Hybrid Capture 2, Polymerase chain reaction (PCR) and Real time Polymerase chain reaction (RT-PCR). The HPV infection can be prevented by vaccination and currently two preventive HPV vaccines based on VLPs are authorized for application. They are totally efficient in preventing infections of HPV 16 and 18 which are mainly high risk HPVs involved in causing genital infections in women .This review reveals the diseases associated with HPV diagnosis, the transmission of HPV and their prevention through effective vaccination.

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Section: • Head Neckmentioning

confidence: 99%

A Review on Role of Human Papilloma Virus (HPV) in Health-Related Diseases

Singh¹,

Ahmad²,

Srivastava³

et al. 2020

AMDHS

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“…Johannes Fibiger, 1926, for experimental production of gastritis and gastric carcinoma; George H. Whipple, 1934, for discovery that a diet rich in liver cures pernicious anemia; Howard W. Florey, 1945, for testing and production of penicillin; F. Peyton Rous, 1966, for discovery of carcinogenic viruses made in 1911; Renato Dulbecco, 1975, for discovery of the interaction between DNA tumor viruses and the genetic material of the host cell; Baruj Benacerraf, 1980, for discovery of the immune response genes; J. Robin Warren, 2005, for co-discovery that stomach ulcers are an infectious disease caused by Helicobacter pylori. [143][144][145][146][147][148][149] Pathologists also have made major contributions to the conjoined fields of cell biology and cell pathology. 10,30,35,36,144,[150][151][152][153][154][155] These contributions have provided a foundation for fundamental insights by basic scientists recognized by the award of six Nobel Prizes in 1908,1974,2002,2004,2012, and 2019.…”

Section: Impact Of Scientific Advances On Pathologymentioning

confidence: 99%

The Texas Society of Pathologists: molded by the legacy of pathology and focused on excellence in medicine for 100 years and beyond

Buja

2020

Baylor University Medical Center Proceedings

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In 1921, 16 Texas pathologists gathered in Dallas, Texas, to found the Texas Society of Pathologists (TSP). The TSP is now the oldest state pathology society in the USA with continuity traced back to its founding 100 years ago. This article aims to both commemorate the TSP centennial and to provide context for the remarkable success of the society. The article takes a look back and a look forward from 1921. The look back focuses on the development of the field of pathology and the maturation of medicine and pathology in the USA and Texas. The look forward encompasses developments in science, technology, American health care policy, and medicine that have impacted Texas pathologists and influenced proactive initiatives of the TSP. The review of the life and times of the TSP highlights the importance of leaders and leadership in shaping outcomes. Complexities and uncertainties of the contemporary health care scene point to the need for continued strong leadership. The successful past century and hopeful future of the TSP are inextricably linked to the guiding principle of the TSP, which is a focus on continual striving for excellence in medicine. KEYWORDS Health care policy; history; Texas society of pathologists "I have great respect for the past. If you don't know where you've come from, you don't know where you are going."-Maya Angelou (1928-2014) "Of necessity an historical account must be largely biographical. Men and their books have built pathology. Yet without a point of view which takes account of the major social movements of general history, no real conception of the historical development of any subject is possible."-Esmond R. Long, MD (1890-1979) "If I have seen further than others, it is by standing upon the shoulders of giants."-Isaac Newton (1642-1726)

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“…After dissociation, the cells were placed in the culture medium, resulting in a suspension of viable cells. The idea of using trypsin to dissociate individual cells is practiced to this day [15].…”

Section: The Twentieth Centurymentioning

confidence: 99%

Historical background of umbilical stem cell culture

Borys-Wójcik

Józkowiak

Stefańska

et al. 2019

Medical Journal of Cell Biology

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Umbilical cord is a waste material, and therefore does not raise ethical concerns related to its use for research and medicine. Stem cells from umbilical cord have a significant advantage over cells from other sources. First, the umbilical cord is an infinite source of stem cells, because it can be taken theoretically during each delivery. Secondly, acquisition of umbilical cord is a non-invasive, safe procedure for mother and child. Thirdly, the transplantation of umbilical cord stem cells is associated with a lower risk of infection and a less-frequent "graft versus host" reaction. In this work, the authors present a historical background of research on the cell from its discovery to modern times characterized by highly advanced methods of obtaining stem cells from umbilical cord and from other sources.Running title: History of umbilical stem cell culture

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Francis Peyton Rous

Abstract: The father of viral oncology, he discovered the first tumor virus and influenced many later scientists, including several Nobel laureates.Decide first. Then turn the page.

Cited by 7 publications

References 8 publications

A Review on Role of Human Papilloma Virus (HPV) in Health-Related Diseases

A Review on Role of Human Papilloma Virus (HPV) in Health-Related Diseases

The Texas Society of Pathologists: molded by the legacy of pathology and focused on excellence in medicine for 100 years and beyond

Historical background of umbilical stem cell culture

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