This paper shows simulations of high waves over different bathymetries to collect statistical information, particularly kurtosis and crest exceedance, that quantifies the occurrence of exceptionally extreme waves. This knowledge is especially pertinent for the design and operation of marine structures, safe ship trafficking, and mooring strategies for ships near the coast. Taking advantage of the flexibility to perform numerical simulations with HAWASSI software, with the aim of investigating the physical and statistical properties for these cases, this paper investigates the change in wave statistics related to changes in depth, breaking and differences between long- and short-crested waves. Three different types of bathymetry are considered: run-up to the coast with slope 1/20, waves over a shoal, and deep open-water waves. Simulations show good agreement in the examined cases compared with the available experimental data and simulations. Then predictive simulations for cases with a higher significant wave height illustrate the changes that may occur during storm events.