Fréquence des maladies auto-immunes chez 218 patients atteints de pathologies thyroïdiennes auto-immunes

Gaches, F.; Delaire, L; Nadalon, S.; Loustaud‐Ratti, Véronique; Vidal, É.

doi:10.1016/s0248-8663(97)80716-3

Cited by 39 publications

(14 citation statements)

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“…For the first case, it was systemic lupus associated with Graves 'disease and for the second Graves' disease associated with anti-phospholipids syndrome. Baili [3] has also described the association as well as Baleva [9], in 4 cases of systemic lupus erythematosus.…”

Section: Discussionmentioning

confidence: 93%

“…The diagnosis of systemic lupus was placed before clinical criteria (a non-deforming non-erosive rheumatoid arthritis of the small joints, unilateral serofibrinous pleurisy) biological (a bicytopenia with leukopenia 3000/mm 3 and haemolytic anaemia to 9.2 g/dl with direct Coombs test positive) and immunologic (positivity of anti Sm). Graves' disease occurred almost two years after diagnosis of treated lupus disease.…”

Section: Discussionmentioning

confidence: 99%

“…In a study conducted by Gaches et al [3], analysing 218 patients suffering from autoimmune thyreopathy, 30 patients, i.e. 13.76% had one or more other autoimmune diseases associated with autoimmune thyreopathy.…”

Section: Discussionmentioning

confidence: 99%

“…It is also possible that these two conditions are concomitant as observed by Baili. [10] In the series of Gaches et al [3] for 17 cases (56.8%), the diagnosis of systemic disease associated was increased concomitantly with that of autoimmune thyroid disease; in 5 patients (16.6%) system disease has preceded thyroid disease and in 8 patients (26.6%) thyroid disease was revealing.…”

Section: Discussionmentioning

confidence: 99%

“…A review of the literature allows considering a common pathogenetic link. There is a genetic field predisposing to the onset of single or multiple dysimmune diseases [3]. However, each of these two conditions has a peculiarity.…”

Section: Discussionmentioning

confidence: 99%

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Association of Graves’ Disease and Systemic Lupus Erythematosus

Diagne

Pouye²,

Faye³

et al. 2015

OJIM

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Summary of Lupus and Basedow Disease Association: The association lupus auto-immune thyroid disease is well known. Lupus is most commonly associated with Hashimoto's thyroiditis. As for Graves' disease, it is most often associated with pernicious anaemia, vitiligo, idiopathic purpura and myasthenia gravis. To our knowledge, we report the first case of lupus associated with Graves' disease in sub-Saharan Africa. Observation: A female patient of 52 years old has been followed since February 2010 for systemic lupus diagnosed on biological and immunological clinical ACR criteria. There was no skin ailment and kidneys involved. Combined treatment with high-dose corticosteroids early and rapid decrease and hydroxychloroquine was established with good clinical and biological evolution. One year later the patient developed thyrotoxicosis syndrome and vascular goitre without exophthalmos associated with the presence of antibodies anti receptor of TSH leading to the diagnosis of Graves' disease. The patient has been treated with synthetic anti-thyroid and beta blocker allowing the regression of clinical symptoms and the normalization of thyroid hormones. Since then, the patient had not shown other signs of systemic affection. Conclusion: Systemic diseases are often associated with autoimmune thyreopathies. But association of lupus with Graves' disease has been rarely described in the literature. One should always watch out for the occurrence of thyroid disease in front of any systemic disease and vice versa.

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Section: Discussionmentioning

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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