Frequency and Antimicrobials Susceptibility Pattern of <i>Staphylococcus aureus</i> Associated with Wound Infections in Surgery Department, Wad Madani Teaching Hospital, Sudan

Abstract

Background: Most community and hospital acquired infections are due to Staphylococcus aureus, these infections involve both local suppurative and systemic conditions. There is an increase in the incidence rates of acquiring resistant strains of Staphylococcus aureus in hospitals and community in Sudan. This study aims to detect frequency of Staphylococcus aureus isolated from surgical-sites infections (SSIs) and traumatic wounds, and to determine susceptibility to commonly used drugs. Methods: Prospective cross-sectional laboratory based study was followed, 250 patients admitted to Surgery Departments at Wad Madani Teaching Hospitals during 2019 and 2020 were recruited; with clinical manifestation of SSIs and or/traumatic wounds. Swab sample was taken from each participant and incubated aerobically on mannitol salt agar. Biochemical tests and 16rRNA gene used for Staphylococcus aureus identification. Antimicrobial susceptibility was accomplished using Kirby Bauer disc diffusion technique. Results: Infection rate of wounds in males and females equal 71% (17/250) and 29% (73/250), while infection rate in the age group of 41 to 60 years was the highest with percentage of 49% (122/250).Staphylococcus aureus constituting 76% (181/238) as predominant isolates. SSIs isolates of Staphylococcus aureus were highly resistant to tested antimicrobials. Meropeneme was the drug of choice with sensitivity of 88% and 100% for SSIs and traumatic wounds isolates respectively. Conclusion: In

Prevalence, resistance profiles and factors associated with skin and soft-tissue infections at Jinja regional referral hospital: A retrospective study

“…The age groups most affected by SSTI were those between 19 and 35 years followed by those between 36 and 59 years with SSTI in the 19–59 group being more likely to be due to MDR pathogens compared to those less than 12 years. This contrasts previous studies that reported a higher likelihood of infection among those above 35 years [ 47 , 48 ]. This might be because this age group is the most active in life, prone to injuries and therefore exposure to antibiotics during treatment of the injuries, increasing their risk for MDR infections.…”

Prevalence, Resistance Profiles and Factors Associated with Skin and Soft-Tissue Infections at Jinja Regional Referral Hospital: A Retrospective Study

“…The age groups most affected by SSTI were those between 19 and 35 years followed by those between 36 and 59 years with SSTI in the 19-59 group being more likely to be due to MDR pathogens than those less than 12 years. This contrasts previous studies that reported a higher likelihood of infection among those above 35 years (24,42). This might be because this age group is the most active in life, prone to injuries and risks that increase their probability of acquiring MDR infections.…”

Frequency of infectious disease caused by Methicillin sensitive Staphylococcus aureus (MSSA) among community and hospital acquired infections in Khartoum State, Sudan

“…S. aureus is one of the main pathogens in hospitals and communities that can cause many infectious diseases, such as mild skin and soft tissue infections, infective endocarditis, osteomyelitis, bacteremia, and fatal pneumonia [10,11].…”