Fresh ginger (Zingiber officinale) has anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines

Chang, Jung San; Wang, Kuo Chih; Yeh, Chia Feng; Shieh, Den En; Chiang, Lien Chai

doi:10.1016/j.jep.2012.10.043

Cited by 282 publications

(217 citation statements)

References 11 publications

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“…Khat, also a stimulant, is an evergreen plant that has amphetamine-like metabolic effects is commonly used for social recreation and to improve work performance [10–12]. It has strong ties to Eastern African and middle-eastern cultures, and is used widely in Ethiopia [9, 13].…”

Section: Introductionmentioning

confidence: 99%

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Daytime Sleepiness, Circadian Preference, Caffeine Consumption and Khat Use among College Students in Ethiopia

Robinson¹,

Gelaye²,

Tadesse

et al. 2014

J Sleep Disor: Treat Care

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Objectives To estimate the prevalence of daytime sleepiness and circadian preferences, and to examine the extent to which caffeine consumption and Khat (a herbal stimulant) use are associated with daytime sleepiness and evening chronotype among Ethiopian college students. Methods A cross-sectional study was conducted among 2,410 college students. A self-administered questionnaire was used to collect information about sleep, behavioral risk factors such as caffeinated beverages, tobacco, alcohol, and Khat consumption. Daytime sleepiness and chronotype were assessed using the Epworth Sleepiness Scale (ESS) and the Horne & Ostberg Morningness /Eveningness Questionnaire (MEQ), respectively. Linear and logistic regression models were used to evaluate associations. Results Daytime sleepiness (ESS≥10) was present in 26% of the students (95% CI: 24.4–27.8%) with 25.9% in males and 25.5% in females. A total of 30 (0.8%) students were classified as evening chronotypes (0.7% in females and 0.9% in males). Overall, Overall, Khat consumption, excessive alcohol use and cigarette smoking status were associated with evening chronotype. Use of any caffeinated beverages (OR=2.18; 95%CI: 0.82–5.77) and Khat consumption (OR=7.43; 95%CI: 3.28–16.98) increased the odds of evening chronotype. Conclusion The prevalence of daytime sleepiness among our study population was high while few were classified as evening chronotypes. We also found increased odds of evening chronotype with caffeine consumption and Khat use amongst Ethiopian college students. Prospective cohort studies that examine the effects of caffeinated beverages and Khat use on sleep disorders among young adults are needed.

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Section: Introductionmentioning

confidence: 99%

“…It has strong ties to Eastern African and middle-eastern cultures, and is used widely in Ethiopia [9, 13]. It is often used among college students and, like caffeine, Khat promotes wakefulness [12]. …”

Section: Introductionmentioning

confidence: 99%

Daytime Sleepiness, Circadian Preference, Caffeine Consumption and Khat Use among College Students in Ethiopia

Robinson¹,

Gelaye²,

Tadesse

et al. 2014

J Sleep Disor: Treat Care

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“…(25) . Referentes aos 19 estudos restantes foram abordadas as seguintes propriedades terapêuticas com pesquisas envolvendo o gengibre: tratamento da náusea induzida por quimioterapia (26) , função para absorção de Ferro, Zinco e Cálcio (27) , analgésico (28) , antidependência contra o uso crônico da morfina (29) , anti-inflamatório (30) , antimicrobiano (31) , combate à ação da artrite reumatoide (32) , aumento da proteólise muscular em patos (33) , tratamento do câncer de mama (14) , citoprotetor (15) , combate ao vírus sincicial respiratório humano (VSR) (34) , combate a sintomas da Doença de Alzheimer (35) , tratamento da fibrose hepática (36) , proteção contra a genotoxicidade (37) , inibição da enzima Angiotensina I (38) , inibição da motilidade do cólon (39) , atenuação da isquemia cerebral (40) , redução da nefrotoxicidade (41) e neuroprotetor (42) , as quais tiveram um estudo cada publicadas durante o período de análise.…”

Section: Resultsunclassified

Análise Sistemática Da Produção Científica Do Zingiber Officinale Roscoe Após a Criação Da Relação Nacional De Plantas Medicinais De Interesse Ao Sistema Único De Saúde

Marmitt¹,

Rempel²,

Goettert³

et al. 2015

ACS

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Arq. Ciênc. Saúde. 2015 out-dez; 22(4) xx-xx Análise sistemática da produção científica do Zingiber Officinale roscoe após a criação da relação nacional de plantas medicinais de interesse ao sistema único de saúde Descritores: Gengibre; Uso Terapêutico; Atenção Primária à Saúde. AbstractIntroduction: Ginger (Zingiber officinale Roscoe) is a native plant from Asia that has been used as a spice and medicinal compound for thousands of years. Many of its compounds have been isolated, identified, and studied due to their pharmacological effects. Objectives: Quantify clinical trials reporting some form of therapeutic action from the use of Z. officinale plant, which are listed on the National Medicinal Plants of Interest to the Unified Health System published between 2010 and 2013 in three scientific databases (SciELO, Science Direct and Springer). Material and Methods: We searched databases using the key search term "Zingiber officinale Roscoe." A total of 757 articles were retrieved. We selected the studies dealing specifically with the term "Zingiber officinale" or related terms such as "ginger," "gingerol," "gingerols," "ginger," and "ginger". Reading the Abstract, we selected those that reported some kind of therapeutic treatment. In the last phase, the selected articles were fully read to search those proving therapeutic potentials from the study of Z. officinale. Results: Thirty articles were included in this review. Six studies reported the antioxidant activity representing the most cited therapy. Conclusion: With the results, it is expected to be possible to guide further research on the species in question, including other diseases not yet explored.Descriptors: Ginger; Therapeutic Use; Primary Health Care.

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“…For example, ginger can alleviate the aches and pains of anticancer chemotherapy treatment [3,4], or act as an anti-inflammatory agent, easing the symptoms of arthritis and other joint conditions [5]. Furthermore, ginger has a powerful antiviral action and is a great remedy for colds [6].…”

Section: Introductionmentioning

confidence: 99%

Ginger-induced Ileal Motility is Modified by Stress: Sex Differences in Rats

Kimoto¹,

Zeredo²,

Ota³

et al. 2015

JFNS

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Abstract:Ginger is widely used as a spice and also an effective herbal medicine to treat gastrointestinal disorders. On the other hand, stress can induce various modulation of digestive motility. Here, we investigated ginger effects on stress-induced motility of the isolated ileum in male and female rats, in vitro. Rats (Wistar, SPF, 7-12 weeks of age, 148-393 g BW) were divided into Control (1G) and 3G groups. 3G stress (every day for 10 min) was loaded by centrifugal apparatus for 1, 3, 15 and 30 days. After the stress loading at each day, a 1 cm-long section of the ileum was isolated under barbiturate anesthesia and fixed to a Magnus-type chamber filled with Tyrode solution. Ileal movements were observed for 60 s following application of zingerone, which is also called vanillylacetone and a key component of the pungency of ginger (0.1-10 µM). Spontaneous motility movements with phasic and tonic patterns were observed in the ileum. The former was a peristalsis-like movement and the latter was a slow fluctuation of the baseline. Ginger induced enhanced effects on the rhythmic phasic motility in relation to amplitude. In the female, 3G gravity loading had no effects on the ginger-induced motility, however, suppressive effect of the ginger-induced phasic movements was clearly observed at day 15 in the male. The present study showed that gravity stress changed ginger-induced effects on phasic ileal motility in the male, but not in the female, indicating that sex differences were observed in the ginger effects modulated by stress loading.

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Fresh ginger (Zingiber officinale) has anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines

Cited by 282 publications

References 11 publications

Daytime Sleepiness, Circadian Preference, Caffeine Consumption and Khat Use among College Students in Ethiopia

Daytime Sleepiness, Circadian Preference, Caffeine Consumption and Khat Use among College Students in Ethiopia

Análise Sistemática Da Produção Científica Do Zingiber Officinale Roscoe Após a Criação Da Relação Nacional De Plantas Medicinais De Interesse Ao Sistema Único De Saúde

Ginger-induced Ileal Motility is Modified by Stress: Sex Differences in Rats

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