Abstract:BackgroundEosinophilic Fasciitis is a rare scleroderma-like connective tissue disorder. No treatment has shown to be effective in randomized trials. The treatment most often reported is combination of moderate to high-dose glucocorticoids (1–1,5mg/kg/day) with weekly methotrexate (MTX), up to 25mg, but often with disappointing results.1,2ObjectivesTo examine the effect and safety of monthly intravenous (IV) high dose MTX in patients wtih eosinophilic fasciits.MethodsPatients with biopsy proven eosinophilic fas… Show more
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