From Challenges to Solution: The Evolving Landscape of Leprosy Management
Lívia Maria Coelho de Carvalho Moreira,
Antônia Carla de Jesus Oliveira,
Luíse Lopes Chaves
et al.
Abstract:Leprosy, caused by Mycobacterium leprae, despite being a curable disease when treated can induce peripheral neuropathy. However, the medicines used in polychemotherapy promote several side effects. Thus, research for the development of new administration systems is an alternative, but there is a lack of preclinical and clinical studies of the systems, where 90.90% have a level of technological maturity 3 and 9.09% level 4. The main issues are associated with deficiencies in vitro and in vivo cultivation method… Show more
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