From Kama Sutra to dot.com: The history, myths and management of premature ejaculation

Astbury-Ward, Edna

doi:10.1080/1468199021000017218

Cited by 10 publications

(8 citation statements)

References 30 publications

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“…Premature ejaculation (PE) and its individual and relationship consequences have been recognized in the literature for centuries. In fact, references to the frustration caused by PE can be found in the Hindu love manual the Kama Sutra , written between the 1st and 4th centuries [1]. Scientific literature had begun mentioning reports of “rapid” or early (premature) ejaculation by the early 1900s [1].…”

Section: Historical Overviewmentioning

confidence: 99%

“…In fact, references to the frustration caused by PE can be found in the Hindu love manual the Kama Sutra , written between the 1st and 4th centuries [1]. Scientific literature had begun mentioning reports of “rapid” or early (premature) ejaculation by the early 1900s [1]. The psychoanalytic view of PE dominated the early 20th century, with emphasis on PE as a male neurosis related to unconscious and unresolved conflicts about women.…”

Section: Historical Overviewmentioning

confidence: 99%

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Premature Ejaculation: On Defining and Quantifying a Common Male Sexual Dysfunction

Broderick

2006

The Journal of Sexual Medicine

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Introduction Premature ejaculation (PE) and its individual and relationship consequences have been recognized in the literature for centuries. PE is one of the most common male sexual dysfunctions, affecting nearly one in three men worldwide between the ages of 18 and 59 years. Until recently, PE was believed to be a learned behavior predominantly managed with psychosexual therapy; however, the past few decades have seen significant advances in understanding its etiology, diagnosis, and management. There is, as yet, no one universally agreed upon definition of PE. Aim To review five currently published definitions of PE. Methods The Sexual Medicine Society of North America hosted a State of the Art Conference on Premature Ejaculation on June 24–26, 2005 in collaboration with the University of South Florida. The purpose was to have an open exchange of contemporary research and clinical information on PE. There were 16 invited presenters and discussants; the group focused on several educational objectives. Main Outcome Measure Data were utilized from the World Health Organization, the American Psychiatric Association, the European Association of Urology, the Second International Consultation on Sexual Dysfunctions, and the American Urological Association. Results The current published definitions of PE have many similarities; however, none of these provide a specific “time to ejaculation,” in part because of the absence of normative data on this subject. While investigators agree that men with PE have a shortened intravaginal ejaculatory latency time (IELT; i.e., time from vaginal penetration to ejaculation), there is now a greater appreciation of PE as a multidimensional dysfunction encompassing several components, including time and subjective parameters such as “control,”“satisfaction,” and “distress.” Conclusion There is a recent paradigm shift away from PE as a unidimensional disorder of IELT toward a multidimensional description of PE as a biologic dysfunction with psychosocial components.

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Section: Historical Overviewmentioning

confidence: 99%

Section: Historical Overviewmentioning

confidence: 99%

Premature Ejaculation: On Defining and Quantifying a Common Male Sexual Dysfunction

Broderick

2006

The Journal of Sexual Medicine

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“…The nerve receptor density of the glans penis is higher than in any other region of the body and has a lower tactile threshold [28], therefore accounting for its higher sensitivity compared with other parts of the body [29]. Topical treatments providing local anaesthesia reduce the sensitivity of the glans penis and delay ejaculation.…”

Section: Discussionmentioning

confidence: 99%

The link between penile hypersensitivity and premature ejaculation

Wyllie

2011

BJU International

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Study Type – Aetiology (case control) Level of Evidence 3b What’s known on the subject? and What does the study add? Very little is known about the aetiology of premature ejaculation. This analysis shows that many PE patients have a heightened penile sensitivity. This information could result in the design and development of new drugs. OBJECTIVES To investigate the correlation between penile hypersensitivity and premature ejaculation (PE), as defined by the criteria identified by the International Society of Sexual Medicine (ISSM). Penile hypersensitivity as a cause of PE is based on historical clinical neurophysiological data and clinical efficacy of the topical desensitizing agent PSD502 in the treatment of PE. PSD502 is a eutectic‐like mixture of two local anaesthetics, lidocaine and prilocaine, whose primary action is to reduce neuronal conduction in sensory afferents. METHODS Historical neurophysiological data was reviewed, together with data from the recent PSD502 clinical trials, including the first published double‐blind clinical trial data evaluating a topical desensitizing agent in a population of men with PE, as per the new ISSM definition. The clinical profile of PSD502, based on its local anaesthetic properties, is used as a surrogate index of the role of sensory afferents in the ejaculatory reflex. RESULTS The published data does not support unequivocally penile hypersensitivity as the cause of PE. Interpretation of the data is hampered by the variability of the populations described as having PE across studies. Data from the PSD502 clinical trials clearly shows that PSD502 increases ejaculatory latency, and improves control and sexual satisfaction when applied topically to men with PE 5 min before intercourse, enabling subjects to delay ejaculation up to six times longer than those who used a placebo. CONCLUSION The clinical profile of PSD502 lends credibility to the penile hypersensitivity hypothesis for PE. The predominant action of local anaesthetics is to reduce neuronal firing in sensory afferents; the clinical profile of PSD502, which shows improvement of ejaculatory function in the absence of a generalized reduction in penile sensitivity, can most readily be explained based on an underlying hypersensitivity in patients with PE.

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“…[7] It consistently affects about one in three men, although two in three men may be affected at some time in their lives. [8] It is suspected that primary PE has a genetic basis.…”

Section: Introductionmentioning

confidence: 99%

Premature ejaculation: A review

Gajjala

Khalidi

2014

Indian J Sex Transm Dis

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Premature ejaculation (PE) is a common male sexual disorder. It is defined by the Diagnostic and statistical manual of mental disorders as “ejaculation occurring, without control, on or shortly after penetration and before the person wishes it, causing marked distress or interpersonal difficulty.[1] Although the timing of intravaginal ejaculatory latency time (IELT) (i.e., time from penetration to ejaculation) is not included in this definition, an IELT of <2 min, or ejaculation occurring before penetration, has been considered consistent with PE.[2] Management involves both the patient and his partner. Therapeutic options should suit both partners and be appropriate to their habit in planning and frequency of intercourse. Follow-up at appropriate intervals to judge efficacy, titrate dosage of pharmacological treatments and ascertain side effects is mandatory.

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From Kama Sutra to dot.com: The history, myths and management of premature ejaculation

Cited by 10 publications

References 30 publications

Premature Ejaculation: On Defining and Quantifying a Common Male Sexual Dysfunction

Premature Ejaculation: On Defining and Quantifying a Common Male Sexual Dysfunction

The link between penile hypersensitivity and premature ejaculation

Premature ejaculation: A review

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