2024
DOI: 10.1177/15500594241294188
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From the Laboratory to the Real-World: The Role of Mismatch Negativity in Psychosis

Mariko Tada,
Sho Yagishita,
Takanori Uka
et al.

Abstract: Mismatch negativity (MMN) has gained attention as a biomarker for psychosis and a translational intermediate phenotype in animal models of psychosis, including rodents and non-human primates. MMN has been linked to global functioning (Global Assessment of Functioning [GAF] score) and prognosis (psychosis onset or remission), suggesting that MMN reflects activities beyond auditory processing alone. This review examines the 45-year history of MMN from the perspective of psychiatric researchers and discusses curr… Show more

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