From two-dimensional to three-dimensional conformal radiotherapy in prostate cancer: An Indian experience

Bhutani, Ritu; Mahantshetty, Umesh; Murthy, Vedang; Shrivastava, SK

doi:10.4103/0019-509x.64718

Cited by 2 publications

(1 citation statement)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The full-text of these papers was reviewed against the inclusion criteria (reasons for exclusion are reported in Additional file 1: Table S1a and b) and 47 finally selected. Study recruitment periods varied considerably with the earliest patients being from 1984 [10] and the latest 2009 [10–13] (Table 1). The populations of individual studies varied from 80 [14] to 7,839 [14, 15] with a combined population of 60,457 (Tables 2, 3 and 4).…”

Section: Resultsmentioning

confidence: 99%

An appraisal of analytical tools used in predicting clinical outcomes following radiation therapy treatment of men with prostate cancer: a systematic review

Raymond¹,

O’Callaghan

Campbell

et al. 2017

Radiat Oncol

View full text Add to dashboard Cite

BackgroundProstate cancer can be treated with several different modalities, including radiation treatment. Various prognostic tools have been developed to aid decision making by providing estimates of the probability of different outcomes. Such tools have been demonstrated to have better prognostic accuracy than clinical judgment alone.MethodsA systematic review was undertaken to identify papers relating to the prediction of clinical outcomes (biochemical failure, metastasis, survival) in patients with prostate cancer who received radiation treatment, with the particular aim of identifying whether published tools are adequately developed, validated, and provide accurate predictions. PubMed and EMBASE were searched from July 2007. Title and abstract screening, full text review, and critical appraisal were conducted by two reviewers. A review protocol was published in advance of commencing literature searches.ResultsThe search strategy resulted in 165 potential articles, of which 72 were selected for full text review and 47 ultimately included. These papers described 66 models which were newly developed and 31 which were external validations of already published predictive tools. The included studies represented a total of 60,457 patients, recruited between 1984 and 2009. Sixty five percent of models were not externally validated, 57% did not report accuracy and 31% included variables which are not readily accessible in existing datasets. Most models (72, 74%) related to external beam radiation therapy with the remainder relating to brachytherapy (alone or in combination with external beam radiation therapy).ConclusionsA large number of prognostic models (97) have been described in the recent literature, representing a rapid increase since previous reviews (17 papers, 1966–2007). Most models described were not validated and a third utilised variables which are not readily accessible in existing data collections. Where validation had occurred, it was often limited to data taken from single institutes in the US. While validated and accurate models are available to predict prostate cancer specific mortality following external beam radiation therapy, there is a scarcity of such tools relating to brachytherapy. This review provides an accessible catalogue of predictive tools for current use and which should be prioritised for future validation.Electronic supplementary materialThe online version of this article (doi:10.1186/s13014-017-0786-z) contains supplementary material, which is available to authorized users.

show abstract

Section: Resultsmentioning

confidence: 99%

An appraisal of analytical tools used in predicting clinical outcomes following radiation therapy treatment of men with prostate cancer: a systematic review

Raymond¹,

O’Callaghan

Campbell

et al. 2017

Radiat Oncol

View full text Add to dashboard Cite

show abstract

Outcomes and Toxicities After Treatment for Men Diagnosed With Localized Prostate Cancer in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis

Kitson-Mills,

Donkor,

Amoako

et al. 2025

Advances in Radiation Oncology

View full text Add to dashboard Cite

From two-dimensional to three-dimensional conformal radiotherapy in prostate cancer: An Indian experience

Abstract: CRT technique with dose escalation results in significant benefit in DFS and OAS in locally advanced prostate cancer.

Cited by 2 publications

References 23 publications

An appraisal of analytical tools used in predicting clinical outcomes following radiation therapy treatment of men with prostate cancer: a systematic review

An appraisal of analytical tools used in predicting clinical outcomes following radiation therapy treatment of men with prostate cancer: a systematic review

Outcomes and Toxicities After Treatment for Men Diagnosed With Localized Prostate Cancer in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis

Contact Info

Product

Resources

About