Frontonasal Dysplasia

Chen, Harold

doi:10.1007/978-1-4614-6430-3_100-2

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“…Skin dimples mostly of cosmetic importance sometimes may be the first sign of a significant developmental defect or an abnormality. Several authors have reported these cutaneous defects in a variety of conditions such as congenital syndromes, skeletal disorders, infections, inborn errors of metabolism, and mechanical trauma (Table ; Figs ). Once a dimple is seen, the clinician should carry out a careful physical examination with particular attention to the number and location of dimples, dysmorphic features, and neurological and orthopedic aspects.…”

Section: Normal Dimplesmentioning

confidence: 99%

Skin dimples

2014

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Skin dimples are a common occurrence in children. Besides being of cosmetic significance, they may give an important clue to an underlying genetic or metabolic problem. A simplified location-based algorithmic approach to diagnose the underlying cause of skin dimples is presented. Clinical significance of medically important dimples, especially sacral dimples, its association with occult spinal dysraphism, and a cost-effective diagnostic strategy for its imaging is discussed.

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Section: Normal Dimplesmentioning

confidence: 99%