Frozen Section for Parotid Surgery: Should It Become Routine?

Abstract

Frozen section in parotid surgery is accurate, inexpensive and may add important information that alters management and improves the outcome. The use of FS routinely in parotid surgery is recommended.

Retrospective Assessment of the Utility of Imaging, Fine-Needle Aspiration Biopsy, and Intraoperative Frozen Section in the Management of Parotid Neoplasms: The Weill Cornell Medical College Experience

“…Contrary to the recommendation by Arabi Mianroodi et al [7] to set a ‘very low' threshold for doing FS in parotid tumor surgery, we found that FS is of limited utility after FNAs consistent with benign disease. This sentiment of setting a low threshold for FS may be secondary to the inclusion of ‘indeterminate salivary gland lesions' in the study.…”

“…Studies such as those done by Schmidt et al [5,8] and Olsen et al [9] have reported the diagnostic accuracy of FS or FNA independently, but the role and value of FS after FNA diagnosis remain unclear. Studies such as those done by Arabi Mianroodi et al [7] report that the threshold for doing FS should be low in order to definitively rule out malignant disease and that FS is indeed cost-beneficial.…”

“…Whether FNA is superior to FS or vice versa remains controversial. Some studies have found FNA to have a higher sensitivity and specificity in detecting malignancy than FS [6], while others have recorded a greater sensitivity and specificity for FS [3,4,5,6,7]. In fact, some pathologists advocate for a touch prep during FS of salivary gland lesions, effectively performing a cytologic examination.…”

“…In fact, some pathologists advocate for a touch prep during FS of salivary gland lesions, effectively performing a cytologic examination. In meta-analyses by Schmidt et al [5,8], FS [area under the summary receiver operating characteristic (AUSROC), 0.99; 95% confidence interval (CI), 0.98-1.00] was found to have a significantly higher diagnostic accuracy than FNA (AUSROC, 0.96; 95% CI, 0.94-0.97) in distinguishing between benign and malignant lesions [5,6,7,8]. Studies such as those done by Schmidt et al [5,8] and Olsen et al [9] have reported the diagnostic accuracy of FS or FNA independently, but the role and value of FS after FNA diagnosis remain unclear.…”

Rak ślinianki przyusznej: analiza kliniczno-patologiczna oraz ocena wyników leczenia

“…Odsetek wyników prawdziwie dodatnich BAC w pracach polskich autorów wahał się od 70% do 75% [11,79]. Na podstawie wyników przedstawionych w literaturze światowej BAC cechuje się czułością od 74% do 85% [1,20,61,117,123]. Pełna zgodność rozpoznania cytologicznego z histopatologicznym w pracy Zbärena i wsp.…”