FT15. Peripheral Artery Disease in Patients With HIV/AIDS: A Nested Case-Control Study

Abstract

vein compression is related with DVT. On the other hand, it may prevent the thrombus from migrating into the pulmonary circulation. The aim of this study was to evaluate the anatomic and clinical risk factors of PE in patients with DVT of the lower extremity (LE).Methods: In the setting of a referral hospital, the patients with DVT underwent duplex ultrasound (DUS) and/or computed tomography (CT) of the LE. PE was evaluated with chest CT. The patients were classified as group 1 (DVT without PE) and group 2 (DVT with PE). We analyzed the anatomic and clinical risk factors associated with PE in patients with DVT. As the anatomic factor, the shortest length between the common iliac artery (CIA) and spinal body (SB) was measured. In statistical analysis, we used independent t-test and multivariable logistic regression model.Results: We examined 114 patients (41.7% men, age 62.76 16.9 years) with DVT with/without PE. The prevalence of concurrent DVT/PE was 52.6%. Neither the risk factors nor blood tests differed significantly between two groups. Of all the assessed patient characteristics (age and sex, body mass index, diabetes, hypertension, history of varicose vein, previous DVT, history of surgery, infection, pneumonia, coronary artery disease, chronic renal failure, and paralysis), the only one factor, infection, was significantly and independently associated with PE (P ¼ .04). The lengths between CIA and SB were 6.7 6 3.5 mm in group 1 and 11.3 6 3.7 mm in group 2, respectively (P < .0001). With receiver operating characteristic curve analysis, 7.6 mm was the cutoff value for the risk of PE in patients with LE DVT.Conclusions: Infection was significantly and independently associated with concurrent DVT/PE. The shorter length between CIA and SB (<7.6 mm) may prevent the PE in patients with DVT. Our results should be further investigated in a larger prospective study.