2023
DOI: 10.1088/1748-605x/ace5fe
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Fucoidan and microtopography on polyvinyl alcohol hydrogels guided axons and enhanced neuritogenesis of pheochromocytoma 12 (PC12) cells

Abstract: Artificial nerve grafts that support axon growth hold promises in promoting nerve regeneration and function recovery. However, current artificial nerve grafts are insufficient to regenerate axons across long nerve gaps. Specific biochemical and biophysical cues are required to be incorporated to artificial nerve grafts to promote neural cell adhesion and guide neurite outgrowth. Polyvinyl alcohol (PVA) nerve conduit has been clinically approved, but the applicability of PVA nerve conduits is limited to short i… Show more

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“…The 1,619 cm −1 peak was attributed to C-C stretching in the benzene ring, ring deformation, and C-C-C deformation. The peak located at 1,575 cm −1 was associated with benzene ring stretching of C=C, as previously reported (Siano et al, 2018;Yao et al, 2023). As previously reported, these two peaks correspond to THC in our hydrogels (Cirrincione et al, 2021).…”
Section: Ftir Analysis Of the Thc Distributionsupporting
confidence: 88%
“…The 1,619 cm −1 peak was attributed to C-C stretching in the benzene ring, ring deformation, and C-C-C deformation. The peak located at 1,575 cm −1 was associated with benzene ring stretching of C=C, as previously reported (Siano et al, 2018;Yao et al, 2023). As previously reported, these two peaks correspond to THC in our hydrogels (Cirrincione et al, 2021).…”
Section: Ftir Analysis Of the Thc Distributionsupporting
confidence: 88%