Full-Thickness-Resection-Device (FTRD)

Richter-Schrag, Hans-Jürgen; Walker, Christine; Thimme, Robert; Fischer, Andreas

doi:10.1007/s00104-015-0091-z

Cited by 61 publications

(29 citation statements)

References 20 publications

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“…However, there are few reports of its use in the rectum; in addition, it presents technical limitations regarding the size of the lesion, and it is difficult to correctly visualize the limits of the polypectomy scar. For these reasons we believe that endoscopists and surgeons should evaluate the best technique jointly in each particular case [37][38][39].…”

Section: Discussionmentioning

confidence: 99%

Transanal endoscopic surgery is effective and safe after endoscopic polypectomy of potentially malignant rectal polyps with questionable margins

et al. 2018

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Section: Discussionmentioning

confidence: 99%

Transanal endoscopic surgery is effective and safe after endoscopic polypectomy of potentially malignant rectal polyps with questionable margins

et al. 2018

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“…For patients who require an endoscopic full-thickness resection (FTRD), for example, a similar problem exists. In these cases, we identify the target tissue to resect and mobilize this tissue using a specially designed cap (FTRD prOVE Cap, Ovesco Endoscopy AG, Tübingen, Germany)[37]. …”

Section: Discussionmentioning

confidence: 99%

First-line endoscopic treatment with over-the-scope clips significantly improves the primary failure and rebleeding rates in high-risk gastrointestinal bleeding: A single-center experience with 100 cases

Richter-Schrag¹,

Glatz²,

Walker³

et al. 2016

WJG

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AIMTo evaluate rebleeding, primary failure (PF) and mortality of patients in whom over-the-scope clips (OTSCs) were used as first-line and second-line endoscopic treatment (FLET, SLET) of upper and lower gastrointestinal bleeding (UGIB, LGIB).METHODSA retrospective analysis of a prospectively collected database identified all patients with UGIB and LGIB in a tertiary endoscopic referral center of the University of Freiburg, Germany, from 04-2012 to 05-2016 (n = 93) who underwent FLET and SLET with OTSCs. The complete Rockall risk scores were calculated from patients with UGIB. The scores were categorized as < or ≥ 7 and were compared with the original Rockall data. Differences between FLET and SLET were calculated. Univariate and multivariate analysis were performed to evaluate the factors that influenced rebleeding after OTSC placement.RESULTSPrimary hemostasis and clinical success of bleeding lesions (without rebleeding) was achieved in 88/100 (88%) and 78/100 (78%), respectively. PF was significantly lower when OTSCs were applied as FLET compared to SLET (4.9% vs 23%, P = 0.008). In multivariate analysis, patients who had OTSC placement as SLET had a significantly higher rebleeding risk compared to those who had FLET (OR 5.3; P = 0.008). Patients with Rockall risk scores ≥ 7 had a significantly higher in-hospital mortality compared to those with scores < 7 (35% vs 10%, P = 0.034). No significant differences were observed in patients with scores < or ≥ 7 in rebleeding and rebleeding-associated mortality.CONCLUSIONOur data show for the first time that FLET with OTSC might be the best predictor to successfully prevent rebleeding of gastrointestinal bleeding compared to SLET. The type of treatment determines the success of primary hemostasis or primary failure.

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“…The FTRD can be mounted over a standard colonoscope 3 . It is composed of a modified 14 t OTSC on a transparent cap featuring a monofilament polypectomy snare loaded on its tip 3 4 ( Fig. 4a , Video ).…”

Section: Discussionmentioning

confidence: 99%

“…4a , Video ). Because the transparent FTRD capʼs volume is greater than that of the OTSC cap (3 cm 3 vs. 0.9 cm 3 ), full-thickness specimens with a median resection surface of 5 cm 2 (range 1.6 cm 2 – 12.9 cm 2 ) 4 5 or a diameter of 3 cm can be resected, respectively 3 ( Fig. 4b , Video ).…”

Section: Discussionmentioning

confidence: 99%

Use of the full-thickness resection device (FTRD) to prevent bleeding after colonic polypectomy in a patient with a left ventricular assist device

et al. 2017

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Background and study aims Treatment of colorectal polyps in patients undergoing permanent anticoagulation is associated with a significantly increased risk of peri-interventional bleeding. This specifically applies to polyps > 1 cm where endoscopic full-thickness resection (EFTR) with the full-thickness-resection device (FTRD) can be taken into consideration as an alternative approach to classical snare polypectomy. For these indications, EFTR appears to be superior to conventional techniques especially in terms of sufficient hemostasis due to the mechanical tissue compression achieved by the FTRDʼs integrated Over-The-Scope Clip (OTSC). This is demonstrated in the following case report of a 59-year-old male with a left ventricular assist device (LVAD) implanted due to congestive heart failure. He presented with intermittent hemorrhage from a large polyp in the ascending colon that was successfully treated via EFTR with the FTRD. A video is included.

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Full-Thickness-Resection-Device (FTRD)

Cited by 61 publications

References 20 publications

Transanal endoscopic surgery is effective and safe after endoscopic polypectomy of potentially malignant rectal polyps with questionable margins

Transanal endoscopic surgery is effective and safe after endoscopic polypectomy of potentially malignant rectal polyps with questionable margins

First-line endoscopic treatment with over-the-scope clips significantly improves the primary failure and rebleeding rates in high-risk gastrointestinal bleeding: A single-center experience with 100 cases

Use of the full-thickness resection device (FTRD) to prevent bleeding after colonic polypectomy in a patient with a left ventricular assist device

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