Función ventricular izquierda en niños después de la reparación exitosa de la coartación aórtica

Balderrabano-Saucedo, Norma; Vizcaíno-Alarcón, Alfredo; Cruz, Lorenzo Reyes-de la; Espinosa-Islas, Gonzalo; Arévalo-Salas, Alexis; Segura-Stanford, Begoña

doi:10.1157/13127843

Cited by 6 publications

(1 citation statement)

References 21 publications

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“…The myocardial performance index, also known as the Tei index 15 , has been the subject of interest since its inception in 1995. One study of 40 normotensive children who had undergone repair of aortic coarctation revealed an abnormal myocardial performance index in almost half the patients, 24 a finding again endorsed by our experience. The index is a valid echocardiographic parameter owing to its ability to assess overall left ventricular performance.…”

Section: Discussionsupporting

confidence: 79%

Myocardial performance after successful intervention for native aortic coarctation

et al. 2010

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Coarctation of the aorta is associated with increased risk for hypertension in adulthood, despite successful repair. The intrinsic mechanisms underscoring hypertension and left ventricular performance in these patients, however, remains to be determined. Our objective was to evaluate left ventricular performance by means of echocardiographic and biochemical parameters at midterm follow-up in normotensive children who have had undergone successful surgical or catheter interventional treatment of coarctation with a residual gradient of less than 20 mmHg at rest. We studied prospectively 14 patients with native aortic coarctation who underwent surgery or balloon angioplasty, the cohort made up of equal numbers of boys and girls, and having a mean age of 8.5 plus or minus 4 years. We also studied 30 age-matched healthy subjects, measuring mitral inflow pulsed wave signals, isovolumic relaxation and contraction times, myocardial performance index parameters, and levels of B-type natriuretic peptide and endothelin-1 in both groups. We found no differences in systolic blood pressure at rest between the patients and their controls. The ventricular septal diastolic dimensions, left ventricular posterior wall dimensions, mitral valve E wave, deceleration time, isovolumic relaxation time, isovolumic contraction time and myocardial performance index were all significantly increased in the patients. Levels of plasma B-type natriuretic peptide and endothelin-1 were also significantly higher in the patients when compared to the control group. We conclude that aortic coarctation is a chronic disease characterized by persistency of myocardial and vascular alterations. The elevated levels of plasma b-type natriuretic peptide and endothelin-1 may be indicative of late onset hypertension after successful treatment of native coarctation in early childhood.

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Section: Discussionsupporting

confidence: 79%

Myocardial performance after successful intervention for native aortic coarctation

et al. 2010

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Cardiac recovery and outcome of neonates and infants presenting with severe aortic coarctation and depressed cardiac function

Valls

Salih

Dadah

et al. 2018

The Egyptian Heart Journal

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ObjectivesCoarctation of the aorta represents 5–8% of all congenital heart diseases. Children with severe coarctation of the aorta may present with significant depression of myocardial function. The aim of this study is to identify short and midterm outcomes of neonates and infants with isolated coarctation of the aorta and depressed left ventricular systolic function with regard to recovery of their cardiac function.MethodsAll patients with isolated coarctation of the aorta who underwent surgical repair between December 2002 and December 2015 were retrospectively reviewed in a cohort study. The patients were divided into 2 groups: (1) Patients with depressed left ventricle systolic function who were found to have an ejection fraction and fractional shortening less than 55% and 25%, respectively, (2) Patients with coarctation of the aorta and normal left ventricle systolic function (Control Group). We reviewed both groups after surgery and compared them in terms of their cardiac function recovery.Results58 patients were included. 25 patients (43%) depressed left ventricle systolic function group, 33 patients (57%) Control Group. There were statistically significant differences in ejection fraction and fractional shortening (p < 0.0001) between the two groups before surgery. Follow-up demonstrated improvement and recovery of ventricular function in most of the patients, six months after surgery there was no more statistical difference between the groups in terms of cardiac function.ConclusionMajority of the patients with isolated coarctation of the aorta and depressed left ventricle systolic function showed improvement of ventricular function within 4 weeks after surgery, except for patients with residual coarctation of the aorta.

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Recovery of Biventricular Function After Catheter Intervention or Surgery for Neonatal Coarctation of the Aorta

et al. 2023

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Función ventricular izquierda en niños después de la reparación exitosa de la coartación aórtica

Cited by 6 publications

References 21 publications

Myocardial performance after successful intervention for native aortic coarctation

Myocardial performance after successful intervention for native aortic coarctation

Cardiac recovery and outcome of neonates and infants presenting with severe aortic coarctation and depressed cardiac function

Recovery of Biventricular Function After Catheter Intervention or Surgery for Neonatal Coarctation of the Aorta

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