Function of the Audiovestibular System in Children with Systemic Lupus Erythematosus

Gad, Ghada I.; Abdelateef, Hanan

doi:10.1007/s11882-014-0446-4

Cited by 12 publications

(12 citation statements)

References 44 publications

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“…A few authors 22 , 23 have described vertigo in patients with SLE and, in all cases, this symptom was always associated with SNHL or tinnitus. Gad and Abdelateef 24 found that vertigo in children with SLE was always associated with cochlear symptoms. However, the incidence of vestibular symptoms may be under-reported due to the slowly progressive onset of these symptoms and compensation by the somatosensory system and vision.…”

Section: Audiovestibular Disorders In Patients With Slementioning

confidence: 99%

Systemic Lupus Erythematosus and hearing disorders: Literature review and meta-analysis of clinical and temporal bone findings

Stadio

Ralli

2017

J Int Med Res

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ObjectiveThis literature review and meta-analysis was performed to evaluate the correlations among hearing and vestibular clinical symptoms, temporal bone findings, and pathological mechanisms in patients with systemic lupus erythematosus (SLE).Study designRelevant papers in the literature were retrospectively reviewed. Clinical hearing aspects in patients with SLE and relevant temporal bone studies in the same field were analyzed.MethodsPubMed and Google Scholar searches were performed using the following keywords: “auto-immune disease,” “systemic lupus erythematosus (SLE),” “hearing loss,” “temporal bone study,” “vertigo,” “dizziness,” “tinnitus,” “ear symptoms,” “treatment,” “diagnosis,” “symptoms,” “etiopathogenesis,” “Wegener granulomatosis,” “Sjogren,” “polyarteritis nodosa,” “Cogan syndrome,” and “granulomatosis.” Also included were reviews in which the following terms were present: “SLE,” “temporal bone,” and “hearing symptoms.”Review and conclusionThis literature review and meta-analysis focused on the pathological mechanisms through which SLE can damage inner ear structures and determinate hearing and vestibular symptoms. The main mechanisms involved in inner ear damage include the autoimmune response, deposition of immune complexes in the vessels and, to a lesser extent, cytotoxic damage.

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Section: Audiovestibular Disorders In Patients With Slementioning

confidence: 99%

Systemic Lupus Erythematosus and hearing disorders: Literature review and meta-analysis of clinical and temporal bone findings

Stadio

Ralli

2017

J Int Med Res

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“…Balance disorders as a consequence of SLE have been observed also in children [37]; however, the incidence of vestibular symptoms may be underestimated due to their slowly progressive onset and consequent compensation by the somatosensory system and vision.…”

Section: Inner Ear Involvement In Autoimmune Diseasesmentioning

confidence: 99%

Audiovestibular Symptoms in Systemic Autoimmune Diseases

Ralli

D’Aguanno

Stadio

et al. 2018

Journal of Immunology Research

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Immune-mediated inner ear disease can be primary, when the autoimmune response is against the inner ear, or secondary. The latter is characterized by the involvement of the ear in the presence of systemic autoimmune conditions. Sensorineural hearing loss is the most common audiovestibular symptom associated with systemic autoimmune diseases, although conductive hearing impairment may also be present. Hearing loss may present in a sudden, slowly, rapidly progressive or fluctuating form, and is mostly bilateral and asymmetric. Hearing loss shows a good response to corticosteroid therapy that may lead to near-complete hearing restoration. Vestibular symptoms, tinnitus, and aural fullness can be found in patients with systemic autoimmune diseases; they often mimic primary inner ear disorders such as Menière's disease and mainly affect both ears simultaneously. Awareness of inner ear involvement in systemic autoimmune diseases is essential for the good response shown to appropriate treatment. However, it is often misdiagnosed due to variable clinical presentation, limited knowledge, sparse evidence, and lack of specific diagnostic tests. The aim of this review is to analyse available evidence, often only reported in the form of case reports due to the rarity of some of these conditions, of the different clinical presentations of audiological and vestibular symptoms in systemic autoimmune diseases.

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“…Vestibular complications are quite common in patients with SLE (19). One study showed that the incidence of abnormal findings on electronystagmography in patients with SLE was significantly higher than in healthy control patients (20).…”

Section: Discussionmentioning

confidence: 99%

Histopathologic Findings in Peripheral Vestibular System From Patients With Systemic Lupus Erythematosus

Kariya

Hızlı

Kaya

et al. 2015

Otology &Amp; Neurotology

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Function of the Audiovestibular System in Children with Systemic Lupus Erythematosus

Cited by 12 publications

References 44 publications

Systemic Lupus Erythematosus and hearing disorders: Literature review and meta-analysis of clinical and temporal bone findings

Systemic Lupus Erythematosus and hearing disorders: Literature review and meta-analysis of clinical and temporal bone findings

Audiovestibular Symptoms in Systemic Autoimmune Diseases

Histopathologic Findings in Peripheral Vestibular System From Patients With Systemic Lupus Erythematosus

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