2024
DOI: 10.1002/acr2.11766
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Functional and Practical Insights Into the Genetic Basis of Takayasu Arteritis

Desiré Casares‐Marfil,
Amr H. Sawalha

Abstract: Takayasu arteritis (TAK) is a rare vasculitis characterized by inflammation of large arteries. Although the exact etiology of TAK remains unclear, a genetic predisposition to the disease has been established. Large‐scale genetic studies have significantly contributed to the identification of genetic variation associated with immune‐mediated diseases. To date, five genome‐wide association studies (GWAS) have been performed in TAK, identifying multiple genetic susceptibility loci across the genome. Here, we summ… Show more

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