Functional constipation in Bangladeshi school aged children: A hidden misty at community

Benzamin, Md.; Karim, Asm Bazlul; Rukunuzzaman, M; Mazumder, Md Wahiduzzaman; Rana, Masud; Alam, Rafiqul; Islam, Mohammad Majharul; Alam, Md. Shafiul; Hossen, Kamal; Yasmin, Afsana; Fathema, Kaniz; Khadga, Mukesh; Aishy, Aisharza Sultana

doi:10.5409/wjcp.v11.i2.160

Cited by 5 publications

(3 citation statements)

References 27 publications

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“…Although not part of the Rome IV criteria for the diagnosis of FC, important clinical feature associations were present in 61% of the children, and abdominal pain at presentation was the most common (44%), representing the highest reported association in the literature. 13 – 15 The clinical importance of this association is considerable and should help in the evaluation of children presenting with constipation and abdominal pain, particularly because constipation should be an important differential of abdominal pain. The normal results of routine screening for CD in our study contrasts with reports indicating an increased incidence of CD in chronic constipation.…”

Section: Discussionmentioning

confidence: 99%

Clinical profile of functional constipation in Saudi children

El Mouzan,

Kambal,

Alabdulkarim

et al. 2024

Ann Saudi Med

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BACKGROUND: Functional constipation (FC) is a common condition in children, and information on the clinical characteristics of FC in Saudi children is scarce. OBJECTIVE: Describe the clinical profile of FC in Saudi children. DESIGN: Retrospective SETTING: Hospital that provides primary, intermediate and tertiary care. PATIENTS AND METHODS: All children diagnosed with FC according to the Rome IV criteria were included and had at least one follow-up clinic visit. Demographic and clinical data collected from medical records included the age at onset, duration of constipation, clinical features, treatment modalities, and factors associated with clinical response. Descriptive statistics and Pearson's chi-squared test were used in the statistical analysis to see how categorical study variables were linked to clinical response. A P value of ≤.05 was used to report statistical significance. MAIN OUTCOME MEASURE: Compliance and clinical response to polyethylene glycol (PEG) compared with lactulose. SAMPLE SIZE: 370 children from 0.1 to 13 years of age. RESULTS: The median (IQR) age of onset was 4 (5) years and less than one year in 14%. The median (IQR) duration of constipation was 4 months (11) and less than two months in 93/370 (25%). Abdominal pain was the most commonly associated feature (44%). Screening for celiac disease and hypothyroidism was negative. A Fleet enema was the most common disimpaction method (54%) and PEG was the most common maintenance medication (63.4%). PEG was significantly better tolerated ( P =.0008) and more effective than lactulose ( P <.0001). Compliance was the only variable significantly associated with clinical response. CONCLUSIONS: PEG was better tolerated and more effective than lactulose in our study, a finding in agreement with the literature. Therefore, PEG should be the drug of choice in the initial management of FC in Saudi children. Prospective studies on the causes of noncompliance are needed to improve the response to treatment. LIMITATIONS: The limitations of retrospective design are missing data, recall bias, and hospital-based limitation, such as missing milder cases treated at the outpatient level. However, the sample size of 370 may have minimized these limitations.

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Section: Discussionmentioning

confidence: 99%

Clinical profile of functional constipation in Saudi children

El Mouzan,

Kambal,

Alabdulkarim

et al. 2024

Ann Saudi Med

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“…The composition of gut microbiota in infants depends on delivery mode [ 34 ] and cesarean delivery was associated with high risk of FC [ 35 – 37 ]. Finally, familiarity is another confirmed risk factor [ 38 – 40 ]. As a matter of fact, in 2010 Ostwani et al published the results of a family study of children with and without functional constipation.…”

Section: What Is the Etiology?mentioning

confidence: 99%

The ten “hard” questions in pediatric functional constipation

Fedele,

Fioretti,

Scarpato

et al. 2024

Ital J Pediatr

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Functional constipation is a common problem in childhood and has a great impact on social, physical, and emotional functioning of affected children and their caregivers. No organic cause of the constipation can be found in approximately 95% of children, defining the “so-called” chronic functional constipation. Its prevalence has been reported to range from 0.7 to 29.6%, with a median of 12%. The diagnosis of functional constipation is exclusively clinical based on the pediatric diagnostic Rome criteria for functional gastrointestinal disorders and does not routinely require laboratory and/or radiological investigations. In case of alarm signs and symptoms that may suggest organic diseases, further investigations can be required. The therapeutic management is based on non-pharmacological and pharmacological approaches. Education, demystification of constipation and reward-based toilet training represent the cornerstones of nonpharmacological management. Disimpaction, maintenance treatment and weaning of medication are all elements of pharmacological treatment. Osmotic laxatives, mainly polyethylene glycol (PEG), are considered the first-choice laxative for both disimpaction and maintenance treatment. The aim of this review is to provide pediatric gastroenterologists with a practical tool to support the clinical and therapeutic management of children and adolescents affected by chronic functional constipation.

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“…It is 8.4%, 3.9%, 17.1%, 18.1%, and 5.6% in China, Japan, India, Indonesia, and Vietnam, respectively [30,41,[50][51][52]. Developing nations such as Bangladesh and Sri Lanka reported that 19% and 8% of children were affected by this disorder, respectively [53,54]. All these data indicate that constipation in children has become equally prevalent among developed countries and LMICs, making it a global health problem that needs to be addressed soon [43,55,56].…”

Section: Epidemiologymentioning

confidence: 99%

Constipation: A Pristine Universal Pediatric Health Delinquent

Chowdhury,

Sinha,

Kumar

et al. 2024

Cureus

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Constipation suffered by children is a global public health problem. Functional constipation (FC) brings about deteriorating effects in the children's lives who suffer from it. The risk factors for the development of constipation include the consumption of a diet low in fiber and high in calories (such as the consumption of fast food), a sedentary lifestyle with a lack of exercise, a family history of constipation, and emotional and psychological stress endured by children in their families. It is one of the most common causes of stomachaches in children. FC may lead to fecal incontinence (FI), anal fissures, recurrent urinary tract infections (RUTI), and enuresis in children. Severe constipation may result in stool becoming rock-hard and inflexible in the rectum, which is clinically identified as fecal impaction. It is imperative to perform clinical evaluation and treatment, including pharmacological (the use of stimulant and osmotic laxatives) and nonpharmacological (education, changes in diet, intervention to promote positive behavior and address any emotional issues, toilet training, and physiotherapy for the pelvic floor) interventions. In the case of refractory patients, neuromodulation, the irrigation of the anal canal, and surgical management may be needed. It is essential to lead a healthy, stress-free lifestyle with plenty of exercise and a balanced diet rich in fiber (such as fruits and vegetables) so children can have regular bowel habits and thrive.

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Functional constipation in Bangladeshi school aged children: A hidden misty at community

Cited by 5 publications

References 27 publications

Clinical profile of functional constipation in Saudi children

Clinical profile of functional constipation in Saudi children

The ten “hard” questions in pediatric functional constipation

Constipation: A Pristine Universal Pediatric Health Delinquent

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