Functional modification of gelatin-based biodegradable composite films: a review

Lou, Lan; Chen, Hongyan

doi:10.1080/19440049.2023.2222844

Cited by 9 publications

(2 citation statements)

References 127 publications

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“…Among them, proteinpolysaccharide biocomposites can enhance the physical, mechanical, and barrier properties of protein-polysaccharide composites due to hydrophobic-hydrophobic and/or electrostatic interactions in their polymer networks [10]. It is also necessary to impart certain antimicrobial and antioxidant properties to composites by adding active substances [11].…”

Section: Introductionmentioning

confidence: 99%

Preparation, Optimization, and Characterization of Bovine Bone Gelatin/Sodium Carboxymethyl Cellulose Nanoemulsion Containing Thymol

Liu,

Shen,

Wang

et al. 2024

Foods

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The aim of this study is to produce a biodegradable food packaging material that reduces environmental pollution and protects food safety. The effects of total solids content, substrate ratio, polyphenol content, and magnetic stirring time on bovine bone gelatin/sodium carboxymethylcellulose nanoemulsion (BBG/SCMC–NE) were investigated using particle size, PDI, turbidity, rheological properties, and zeta potential as evaluation indexes. The micro, structural, antioxidant, encapsulation, and release properties were characterized after deriving its optimal preparation process. The results showed that the nanoemulsion was optimally prepared with a total solids content of 2%, a substrate ratio of 9:1, a polyphenol content of 0.2%, and a magnetic stirring time of 60 min. SEM showed that the nanoemulsion showed a dense and uniform reticulated structure. FTIR and XRD results showed that covalent cross-linking of proteins and polysaccharides altered the structure of gelatin molecular chains to a more compact form but did not change its semi-crystalline structure. DSC showed that the 9:1 BBG/SCMC–NE had a higher thermal denaturation temperature and greater thermal stability, and its DPPH scavenging rate could reach 79.25% and encapsulation rate up to 90.88%, with excellent slow-release performance. The results of the study provide basic guidance for the preparation of stable active food packaging with excellent properties.

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Section: Introductionmentioning

confidence: 99%

Preparation, Optimization, and Characterization of Bovine Bone Gelatin/Sodium Carboxymethyl Cellulose Nanoemulsion Containing Thymol

Liu,

Shen,

Wang

et al. 2024

Foods

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“…Furthermore, it has been reported that the main characteristics of gelatin films can be improved through the incorporation of nanoparticles (NPs) [ 1 ]. Several NPs, both metals and metal oxides as well as clay NPs, have been loaded on gelatin films, with consequent improvement of barrier and mechanical properties [ 1 , 14 , 15 , 16 ]. However, relatively high concentrations of nanoparticles have been reported to reduce the mechanical strength of nanocomposite films [ 17 ].…”

Section: Introductionmentioning

confidence: 99%

The Role of WO3 Nanoparticles on the Properties of Gelatin Films

Rubini,

Menichetti,

Cassani

et al. 2024

Gels

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Gelatin films are very versatile materials whose properties can be tuned through functionalization with different systems. This work investigates the influence of WO3 nanoparticles on the swelling, barrier, mechanical, and photochromic properties of gelatin films. To this purpose, polyvinylpirrolidone (PVP)-stabilized WO3 nanoparticles were loaded on gelatin films at two different pH values, namely, 4 and 7. The values of swelling and solubility of functionalized films displayed a reduction of around 50% in comparison to those of pristine, unloaded films. In agreement, WO3 nanoparticles provoked a significant decrease in water vapor permeability, whereas the decrease in the values of elastic modulus (from about 2.0 to 0.7 MPa) and stress at break (from about 2.5 to 1.4 MPa) can be ascribed to the discontinuity created by the nanoparticles inside the films. The results of differential scanning calorimetry and X-ray diffraction analysis suggest that interaction of PVP with gelatin reduce gelatin renaturation. No significant differences were found between the samples prepared at pH 4 and 7, whereas crosslinking with glutaraldehyde greatly influenced the properties of gelatin films. Moreover, the incorporation of WO3 nanoparticles in gelatin films, especially in the absence of glutaraldehyde, conferred excellent photochromic properties, inducing the appearance of an intense blue color after a few seconds of light irradiation and providing good resistance to several irradiation cycles.

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Shell Formulation in Soft Gelatin Capsules: Design and Characterization

Naharros‐Molinero,

Caballo‐González,

de la Mata

et al. 2023

Adv Healthcare Materials

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Soft gelatin capsules are the most widely used pharmaceutical form after tablets. The active components, active pharmaceutical ingredients or nutrients are dissolved or suspended in a liquid or semi‐solid fill, which is covered with a gelatin shell. Several factors can modify the properties of the gelatin shell and subsequently affect their operative handling during manufacturing process and the stability of the soft gelatin capsules. Three elements appear to be crucial: the shell formulation (type and content of the different components such as gelatin ‐source, extraction method‐, plasticizers, or additives); the manufacture and storage conditions (temperature, humidity, light) as well as the interactions between fill‐shell formulas. Mechanical and thermal analysis arise as straightforward but highly useful tools to monitor the properties of the gelatin shell. This review provides an updated overview on the shell formulation and design. Additionally, it presents the uses of mechanical and thermal techniques to characterize and evaluate the impact of different parameters on the gelatin behavior over the production and stability of these pharmaceutical forms. This will help to detect changes that are yet not visible by visual inspection ensuring a suitable finished product over its shelf‐life.This article is protected by copyright. All rights reserved

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Functional modification of gelatin-based biodegradable composite films: a review

Cited by 9 publications

References 127 publications

Preparation, Optimization, and Characterization of Bovine Bone Gelatin/Sodium Carboxymethyl Cellulose Nanoemulsion Containing Thymol

Preparation, Optimization, and Characterization of Bovine Bone Gelatin/Sodium Carboxymethyl Cellulose Nanoemulsion Containing Thymol

The Role of WO3 Nanoparticles on the Properties of Gelatin Films

Shell Formulation in Soft Gelatin Capsules: Design and Characterization

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