Functional photostability and cutaneous compatibility of bioactive UVA sun care products

Cutaneous biocompatible rutin-loaded gelatin-based nanoparticles increase the SPF of the association of UVA and UVB filters

“…The o-dihydroxy structure in the B ring; the 2,3 double bond in conjugation with a 4-oxo function in the C ring and the 7-and 5-OH groups with 4-oxo function in A and C rings (Oliveira et al, 2015). Additionally, these polyphenol reactive sites can interact with gelatin and form C\ \N covalent bonds as the cross-linking in a gelatin matrix.…”

Gelatin-based microspheres crosslinked with glutaraldehyde and rutin oriented to cosmetics

“…The basal values were determined before patch application, and further measurements were made at 24 hours, 2 hours after its removal. To minimize the effect of inter-individual variability, the results were analyzed as the ratio between the values obtained after patch application and the basal values (Oliveira et al, 2015;Peres et al, 2016).…”

“…For all the variables, the ratio between the values after TABLE III -Surface area, volume and pore sizes, true density, diameters of 10%, 50%, 90% and average diameter by laser diffraction of gelatin and gelatin microspheres the patch application and the basal values was, hence, close to 1 (Figure 4). The ratio was used to decrease the inter-individual variability impact (Oliveira et al, 2015).…”

“…For example, our research group observed that an O/W emulsion containing 0.1% rutin in association with 3.5% octyl methoxycinnamate and 1.0% benzophenone-3 developed a significant improvement of the in vitro sun protective properties in comparison with a similar preparation without the flavonoid de Oliveira et al, 2015). Oliveira et al (2015) additionally described the positive interaction of 0.1% rutin and 6.0% BZ3 in an O/W emulsion. Authors observed that the flavonoid contributed with the elevation of the in vitro SPF of 24 to 33.…”

Segurança e eficácia antioxidante pré-clínica e clínica de etossomas contendo rutina de orientação de uso cosmético

“…Devido à sua intensa atividade antioxidante, a rutina é empregada na indústria alimentícia, na prevenção ou tratamento da insuficiência venosa ou linfática e da fragilidade ou permeabilidade capilar, além de ser empregada na prevenção aos danos causados pela radiação UV (GUARDIA et al, 2001;VELASCO et al, 2008;BABY et al, 2008 (Oliveira et al, 2015).…”