Functional Results After Microsurgical Resection of Brain Stem Cavernous Malformations (Retrospective Study of a 12 Patient Series and Review of the Recent Literature)

Sindou, Marc; Yada, José Zanoni; Salord, F

doi:10.1007/s007010070069

Cited by 59 publications

(29 citation statements)

References 30 publications

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“…These results compare well with the results of previous series (Table 2). 3,5,8,[15][16][17]21,24,26,31,33,36,38,41 Differences in tumor location, dimension, histology, surgical technique, and grades of resection, along with the absence of a specific subgroup analysis in terms of different surgical approaches, make any comparison difficult. In addition, in our series the small sample size of each group of patients, where different grades of resection could be achieved, prevents further analysis and making definitive conclusions.…”

Section: Discussionmentioning

confidence: 99%

The lateral infratrigeminal transpontine window to deep pontine lesions

Ferroli

Schiariti

Cordella

et al. 2015

JNS

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S urgery of intraaxial brainstem lesions has been shown to be feasible and is now being performed in selected patients despite the risk of functional brainstem damage. 4,15,20,31 There are many variables that affect the results of this surgery such as patient selection, surgical techniques, and available technologies. In addition, there is currently no consensus surrounding the decision-making process that guides the surgeon to choose this approach. This is particularly true when this surgery is under consideration for deep pontine lesions that require a brainstem incision to be exposed. In fact, the pons remains one of the most protected and inaccessible areas of the brain because its exposition is obstructed by the cerebellum posteriorly, by the petrous bone laterally, and by septic nasal cavities abbreviatioNs CMAP = compound muscle action potential; CN = cranial nerve; DTI = diffusion tensor imaging; GTR = gross-total resection; MEP = motor evoked potential; mRS = modified Rankin Scale; SSEP = somatosensory evoked potential; STR = subtotal resection.

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Section: Discussionmentioning

confidence: 99%

The lateral infratrigeminal transpontine window to deep pontine lesions

Ferroli

Schiariti

Cordella

et al. 2015

JNS

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“…Brainstem cavernomas are associated with significant focal impairment caused by hemorrhages leading to facial nerves damage (15) . Table 2 shows the clinical manifestation in the majority of series.…”

Section: Discussionmentioning

confidence: 99%

“…9 Symptomatic brainstem hemorrhage, sudden onset of neurological damage Sindou et al (15) 12 Patients were referred to surgery because of a sudden or rapidly progressive deterioration of the neurological status. All patients had one or more bleeds…”

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confidence: 99%

Brainstem cavernomas: a surgical challenge

Aguiar

Zicarelli

Isolan

et al. 2012

Einstein (São Paulo)

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Objective: The authors show their experience with brainstem cavernomas, comparing their data with the ones of a literature review. Methods: From 1998 to 2009, 13 patients harboring brainstem cavernomas underwent surgical resection. All plain films, medical records and images were reviewed in order to sample the most important data regarding epidemiology, clinical picture, radiological findings and surgical outcomes, as well as main complications. Results: The mean age was 42.4 years (ranging from 19 to 70). No predominant gender: male-to-female ratio, 6:7. Pontine cases were more frequent. Magnetic resonance imaging was used as the imaging method to diagnose cavernomas in all cases. The mean follow-up was 71.3 months (range of 1 to 138 months). Clinical presentation was a single cranial nerve deficit, VIII paresis, tinnitus and hearing loss (69.2%). All 13 patients underwent resection of the symptomatic brainstem cavernoma. Complete removal was accomplished in 11 patients. Morbidity and mortality were 15.3 and 7.6%, respectively. Conclusions: Cavernomas can be resected safely with optimal surgical approach (feasible entry zone) and microsurgical techniques, and the goal is to remove all lesions with no cranial nerves impairment. Keywords

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“…In general, the annual risk of hemorrhage for a brainstem CM is reported to be between 2% and 21%. 33,57 This generalization, however, is usually agreed to be insufficient on its own to determine the absolute need for operative intervention when such a lesion is incidentally discovered.…”

Section: Clinical Decision Makingmentioning

confidence: 99%

Operative management of brainstem cavernous malformations

Asaad

Walcott²,

Nahed³

et al. 2010

FOC

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Brainstem cavernous malformations (CMs) are complex lesions associated with hemorrhage and neurological deficit. In this review, the authors describe the anatomical nuances relating to the operative techniques for these challenging lesions. The resection of brainstem CMs in properly selected patients has been demonstrated to reduce the risk of rehemorrhage and can be achieved relatively safely in experienced hands.

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Functional Results After Microsurgical Resection of Brain Stem Cavernous Malformations (Retrospective Study of a 12 Patient Series and Review of the Recent Literature)

Cited by 59 publications

References 30 publications

The lateral infratrigeminal transpontine window to deep pontine lesions

The lateral infratrigeminal transpontine window to deep pontine lesions

Brainstem cavernomas: a surgical challenge

Operative management of brainstem cavernous malformations

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