Functional tests in patients with ischemic heart disease

Avram, Rodica; Nechita, Alexandru Cristian; Popescu, Marius; Teodorescu, Matei; Ghilencea, Liviu-Nicolae; Turcu, Diana Veronica; Lechea, Elena; Maher, Sean Martin; Bejan, Gabriel Cristian; Berteanu, Mihai

doi:10.25122/jml-2019-0142

“…These tests are key components of health assessment in the elderly, which are susceptible to frailty and functional decline [4] , but have also been used in the diagnosis of functional loss of younger patients as well [5] . The association between functional status and adverse outcomes has been previously observed in stable coronary artery disease [6] , after myocardial heart infarction [7] , and heart failure [2] . In open chest heart surgery (OHS), risk scores are designed to predict mortality, in which the European System for Cardiac Operative Risk Evaluation (Euroscore II) is one of the most employed worldwide [8] .…”

Section: Introductionmentioning

confidence: 78%

Physical performance tests and in-hospital outcomes in elective open chest heart surgery

Santana¹,

Mediano²,

Kasal³

2023

IJC Heart & Vasculature

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“…Фактори, пов'язані з короткостроковою смертністю госпіталізованих пацієнтів із ІХС та ХОЗЛ, включають літній вік, прогресування дихальної недостатності, що потребує штучної вентиляції легень, тяжкість захворювання та супутні захворювання. Для довгострокового прогнозування смертності в попередніх дослідженнях були визначені такі фактори, як вік, задишка, обструкція повітряного потоку та численні супутні захворювання [5].…”

Section: вступunclassified

“…Епідеміологічні дослідження показують, що серед осіб з тривогою скарги на порушення сну мають високу поширеність в загальній популяції [5]. Безсоння є одним з головних предикторів виникнення тривоги, яке пов'язане з психічним гіперзбудженням, занепокоєнням та негативними думками [6].…”

Section: стаття є фрагментом ініціативної науково-дослідної роботи ка...unclassified

Potential for Pathogenetic Correction of Protease-Antiprotease System Imbalance in Patients With Comorbidity of Stable Angina Pectoris of the Ii-Iii Functional Class and Stage Ii-Iii Chronic Obstructive Pulmonary Disease

Dotsenko,

Kraidashenko

2023

Act. Probl. of the Modern Med.

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The aim of this study is to assess the clinical effectiveness of the therapy including exogenous L-arginine and statins under the comorbidity of stable angina pectoris of the II-III functional class and chronic obstructive pulmonary disease of the II-III stage. Materials and methods. The study included 50 patients with coronary heart disease and chronic obstructive pulmonary disease (mean age 57 years; male/female ratio 78/22%). In order to assess the clinical effectiveness of the therapy for combined cardiopulmonary pathology, the patients were randomized into 2 subgroups: subgroup 1 included 25 patients who took metabolitotropic medication under high-intensity statin therapy (the basic therapy included L-arginine and rosuvastatin as a hypolipidemic agent in a dose of 20 mg/day); subgroup 2 included 25 patients who received only basic therapy under moderately intensive statin therapy (daily doses of atorvastatin 20 mg, rosuvastatin 10 mg)). The groups were comparable in terms of gender distribution and demographic characteristics. Comparative analysis of smoking experience, initial smoking age and smoking history did not differ significantly between the groups. After 12±1 weeks, a control examination was carried out. Results. The analysis of the ratio of the MMP-9 activity level before and after the therapy showed that the level of MMP-9 expression decreased by 43.28% (p<0.05) in the 1st subgroup and by 13.18% in the 2nd subgroup until the end of the therapy. TIMP activity after 12 weeks of the treatment was +33.11% (p<0.05) and +11.27% for the 1st and 2nd subgroups respectively. The difference between subgroups 1 and 2 in the level of the CRP marker before and after the therapy was -45.65% (p<0.05) and -9.09%, respectively. 76% of people from the 1st subgroup reached the target level of healthy people before the completion of the therapy that is significantly higher than the similar indicator in the 2nd subgroup (32%) at χ2=8.05, p<0.01. Conclusions: The application of L-arginine alongside high-intensity statin therapy for patients presenting with stable angina pectoris of the II-III functional class and stage II-III chronic obstructive pulmonary disease (COPD) resulted in more notable positive changes in the modulation of protease-antiprotease status disorders. This was evidenced by a reduction in the heightened expression of MMP-9 and an increase in the level of TIMP during the course of treatment.

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“…Gait is not only one of the basic forms of rehabilitation for these patients but also has a significant predictive value. The distance covered and the gait velocity in the walking test by patients with cardiovascular diseases are important indicators of their death risk [1][2][3][4].…”

Section: Introductionmentioning

confidence: 99%

Do Mechatronic Poles Change the Gait Technique of Nordic Walking in Patients with Ischemic Heart Disease?

Szpala

¹

,

Winiarski

²

,

Kołodziej

³

et al. 2023

Applied Bionics and Biomechanics

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The study aimed to compare the technique of normal gait with the Nordic walking (NW) gait with classical and mechatronic poles in patients with ischemic heart disease. It was assumed that equipping classical NW poles with sensors enabling biomechanical gait analysis would not cause a change in the gait pattern. The study involved 12 men suffering from ischemic heart disease (age: 66.2 ± 5.2 years, body height: 173.8 ± 6.74 cm; body mass: 87.3 ± 10.89 kg; disease duration: 12.2 ± 7.5 years). The MyoMOTION 3D inertial motion capture system (Noraxon Inc., Scottsdale, AZ, USA) was used to collect biomechanical variables of gait (spatiotemporal and kinematic parameters). The subject’s task was to cover the 100 m distance with three types of gait-walking without poles (normal gait), walking with classical poles to NW, and walking with mechatronic poles from the so-called preferred velocity. Parameters were measured on the right and left sides of the body. The data were analyzed using two-way repeated measures analysis of variance with the between-subject factor “body side.” Friedman’s test was used when necessary. For most kinematic parameters, with the exception of knee flexion–extension ( p = 0.474 ) and shoulder flexion–extension ( p = 0.094 ), significant differences were found between normal and walking with poles for both the left and right side of the body and no differences due to the type of pole. Differences between the left and right movement ranges were identified only for the ankle inversion–eversion parameter (gait without poles p = 0.047 ; gait with classical poles p = 0.013 ). In the case of spatiotemporal parameters, a reduction in the cadence step value using mechatronic poles and the stance phase using classical poles compared to normal walking was observed. There was also an increase in the values for step length and step time regardless of the type of poles, stride length, and swing phase when using classical poles and stride time when using mechatronic poles. The differences between the right and left sides of the measurement occurred when walking with both types of poles for single support (gait with classical poles p = 0.003 ; gait with mechatronic poles p = 0.030 ), stance phase (gait with classical poles p = 0.028 ; gait with mechatronic poles p = 0.017 ) and swing phase (gait with classical poles p = 0.028 ; gait with mechatronic poles p = 0.017 ). Mechatronic poles can be used in the study of the biomechanics of gait in real-time with feedback on its regularity because no statistically significant differences were found between the NW gait with classical and mechatronic poles in the studied men with ischemic heart disease.

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Functional tests in patients with ischemic heart disease

Cited by 4 publications

References 35 publications

Physical performance tests and in-hospital outcomes in elective open chest heart surgery

Physical performance tests and in-hospital outcomes in elective open chest heart surgery

Potential for Pathogenetic Correction of Protease-Antiprotease System Imbalance in Patients With Comorbidity of Stable Angina Pectoris of the Ii-Iii Functional Class and Stage Ii-Iii Chronic Obstructive Pulmonary Disease

Do Mechatronic Poles Change the Gait Technique of Nordic Walking in Patients with Ischemic Heart Disease?

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