Functionalized Chitosan and Its Use in Pharmaceutical, Biomedical, and Biotechnological Research

Enescu, Daniela; Olteanu, C.

doi:10.1080/00986440801958808

Cited by 60 publications

(45 citation statements)

References 125 publications

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“…22 Particularly in biomaterials research, they have been found to have enhanced healing rates and tissue-repair strengths. [23][24][25] The casting solution of chitosan with bioactive compounds have been widely studied via the incorporation of drugs, proteins, dyes, [26][27][28] essential oils, 29,30 and phenolic compounds. 31 Chitosan films have been incorporated with thyme oil for potential wound-healing applications.…”

Section: Introductionmentioning

confidence: 99%

Eucalyptus oil nanoemulsion-impregnated chitosan film: antibacterial effects against a clinical pathogen, Staphylococcus aureus, in vitro

Sugumar¹,

Mukherjee²,

Chandrasekaran³

2015

IJN

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Eucalyptus oil ( Eucalyptus globulus ) nanoemulsion was formulated using low-and high-energy emulsification methods. Development of nanoemulsion was optimized for system parameters such as emulsifier type, emulsifier concentration, and emulsification methods to obtain a lower droplet size with greater stability. The minimized droplet diameter was achieved using the high-energy method of ultrasonication. Tween 80 was more effective in reducing droplet size and emulsion appearance when compared to Tween 20. Stable nanoemulsion was formulated with Tween 80 as a surfactant, and the particle size was found to be 9.4 nm (1:2 v/v). The eucalyptus oil nanoemulsion was impregnated into chitosan (1%) as a biopolymer in varying concentrations. Further, the film was characterized by moisture content, microscopic study, X-ray diffraction, and Fourier transform infrared spectroscopy. Also, the film with and without nanoemulsion was evaluated against Staphylococcus aureus . The nanoemulsion-impregnated chitosan film showed higher antibacterial activity than chitosan film. These results support the inclusion of nanoemulsion-impregnated chitosan film in wound management studies.

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Section: Introductionmentioning

confidence: 99%

Eucalyptus oil nanoemulsion-impregnated chitosan film: antibacterial effects against a clinical pathogen, Staphylococcus aureus, in vitro

Sugumar¹,

Mukherjee²,

Chandrasekaran³

2015

IJN

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“…Chitosan, an unbranched cationic biopolymer, has amounts of hydroxyl and amido groups, which can form strong coordinate bond with metal ions. The strong interaction between chitosan molecules and LDHs particles is supposed to occur during the growth of LDHs crystal, which can lead to special size and morphology [31,32].…”

Section: Introductionmentioning

confidence: 99%

Preparation and characterization of cetirizine intercalated layered double hydroxide and chitosan nanocomposites

Nejati

Keypour

Nezhad

et al. 2015

Journal of the Taiwan Institute of Chemical Engineers

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“…Chitosan and its derivatives have been used as food (Shahidi & Synowiecki, 1991), cosmetics (Ravi Kumar, Muzzarelli, Muzzarelli, Sashiwa, & Domb, 2004), and in biomedicine (Enescu & Olteanu, 2008). Further, chitosan has been used as a bioactive material due to its biodegradable, non-toxic, and non-allergenic characteristics (Dutta, Dutta, & Tripathi, 2004;Kurita, 1998).…”

Section: Introductionmentioning

confidence: 99%

Inhibitory effects of chitooligosaccharides on degranulation and cytokine generation in rat basophilic leukemia RBL-2H3 cells

Vo¹,

Kong²,

Kim³

2011

Carbohydrate Polymers

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Functionalized Chitosan and Its Use in Pharmaceutical, Biomedical, and Biotechnological Research

Cited by 60 publications

References 125 publications

Eucalyptus oil nanoemulsion-impregnated chitosan film: antibacterial effects against a clinical pathogen, Staphylococcus aureus, in vitro

Eucalyptus oil nanoemulsion-impregnated chitosan film: antibacterial effects against a clinical pathogen, Staphylococcus aureus, in vitro

Preparation and characterization of cetirizine intercalated layered double hydroxide and chitosan nanocomposites

Inhibitory effects of chitooligosaccharides on degranulation and cytokine generation in rat basophilic leukemia RBL-2H3 cells

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