Functionalized multiwalled carbon nanotube-ethosomes for transdermal delivery of ketoprofen: Ex vivo and in vivo evaluation

Yang, Lijuan; Chen, Weibin; Chen, Yuan; Qiu, Yuqin; Yi, Jun; Li, Xiaofang; Lin, Qian; Guo, Bohong

doi:10.1016/j.jddst.2022.103098

Cited by 5 publications

(2 citation statements)

References 70 publications

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“…Overall, the study results suggested that the f‐MWCNTs composite ethosomes are a promising SDD system. [ 128 ]…”

Section: Inorganic Nanocarriersmentioning

confidence: 99%

Progress in Lipid and Inorganic Nanocarriers for Enhanced Skin Drug Delivery

Albakr,

Du,

Zhang

et al. 2024

Advanced NanoBiomed Research

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New advancements in nanocarrier technologies are revolutionizing the delivery of drugs through the skin, allowing for precise treatment with better absorption, stability, and bioavailability. This review investigates lipid and inorganic nanocarriers like liposomes, ethosomes, and inorganic nanoparticles and assesses their potential for delivering drugs through the skin. It emphasizes the mechanisms that enable controlled release and deeper skin penetration, which are crucial for ensuring effectiveness in clinical applications. The review synthesizes existing research, acknowledging that only few nanocarriers are successfully deployed in clinical settings. By offering a comprehensive overview, it sheds light on the progress and future obstacles to using nanocarriers for drug delivery through the skin.

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“…Overall, the study results suggested that the f‐MWCNTs composite ethosomes are a promising SDD system. [ 128 ]…”

Section: Inorganic Nanocarriersmentioning

confidence: 99%

Progress in Lipid and Inorganic Nanocarriers for Enhanced Skin Drug Delivery

Albakr,

Du,

Zhang

et al. 2024

Advanced NanoBiomed Research

View full text Add to dashboard Cite

show abstract

“…Ex vivo results showed a fast skin penetration rate. Anyway, the f-MWCNTs-KP-ES nanocarriers had successfully prolonged the release of ketoprofen in vivo and caused no adverse effect on the observed rat skin [ 172 ].…”

Section: Carbon Nanotubes Cntsmentioning

confidence: 99%

Recent Development of Nanomaterials for Transdermal Drug Delivery

et al. 2023

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Nano-engineered medical products first appeared in the last decade. The current research in this area focuses on developing safe drugs with minimal adverse effects associated with the pharmacologically active cargo. Transdermal drug delivery, an alternative to oral administration, offers patient convenience, avoids first-pass hepatic metabolism, provides local targeting, and reduces effective drug toxicities. Nanomaterials provide alternatives to conventional transdermal drug delivery including patches, gels, sprays, and lotions, but it is crucial to understand the transport mechanisms involved. This article reviews the recent research trends in transdermal drug delivery and emphasizes the mechanisms and nano-formulations currently in vogue.

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