Functionalized N-hydroxypropyl trimethylammonium chloride chitosan as an ICG/DOX co-delivery nanocarriers for targeted and chemo-photothermal combination therapy
This study presents a nanoparticle system of Polymer, DOX, ICG, and HA for CD44 receptor targeting. In mice, the nanoparticles exhibited dual-responsive drug release behavior, triggered by tumor acidity and heat generated by the activated dye.
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