Functionally modified cross-linked molecularly imprinted resins: separation and purification of camptothecin and its theoretical study

Application of Molecular Imprinting Technique in Separation and Detection of Natural Products

“…However, it is difficult to isolate and extract CPT from Camptotheca acuminata due to the diversity and similarity of other components in camptotheca acuminata. Ma et al [29] prepared super-crosslinked molecularly imprinted resin (MIR) using chloromethylated polystyrene resin as the carrier through Friedel-Crafts reaction after crosslinking and surface imprinting. The prepared MIRs are grafted with a large amount of active group phenol and have good hydrophilicity, which is conducive to the application in water environment.…”