Fungal endocarditis after valve replacements

Chaudhuri, M. Ray

doi:10.1016/s0022-5223(19)42363-5

Cited by 40 publications

(5 citation statements)

References 12 publications

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“…summarises some clinical details for 124 patients with Aspergillus endocarditis or aortitis following heart surgery [4,8–91]. The median age of these patients was 43.5 (range 0.8–71) years.…”

Section: Literature Reviewmentioning

confidence: 99%

Post-operative aspergillosis

Pasqualotto

Denning

2006

Clinical Microbiology and Infection

160

173

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While invasive aspergillosis occurs typically in severely immunocompromised patients, cases of surgical site infection have been reported in immunocompetent individuals. The Medline, LILACS and EMBASE databases were searched for descriptions of cases of post-operative aspergillosis, and references from relevant articles and conference abstracts were reviewed. More than 500 cases of post-operative aspergillosis were found. Cardiac surgery (n = 188), ophthalmological surgery (n > 90) and dental surgery (n > 100) were associated with the majority of cases. Other cases involved wound infections (n = 22), bronchial infections (n = 30), mediastinitis (n = 11), pleural aspergillosis (n = 1), infections following orthopaedic surgery (n = 42), vascular prosthetic surgery (n = 22), breast surgery (n = 5), abdominal surgery (n = 10) and neurosurgery (n = 25). In most patients, the source was presumed to be airborne infection during the surgical procedure. Prevention of these infections requires special care of the ventilation system in the operating room. Successful treatment requires rapid diagnosis, surgical debridement and antifungal therapy, often with voriconazole. In order to improve the outcome, better diagnostic methods are needed, particularly for cases of endocarditis and aortitis.

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Section: Literature Reviewmentioning

confidence: 99%

Post-operative aspergillosis

Pasqualotto

Denning

2006

Clinical Microbiology and Infection

160

173

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“…In einer 97 Beobachtungen einer Endokarditis nach Implantation von Kugelklappenprothesen umfassenden Zusammenstellung aus der Literatur (Shafer und Hall 1970) betrug der Anteil der Staphylokokken-Infektionen etwa 60 %. Pilz-Infektionen wurden in den letzten Jahren von verschiedener Seite mitgeteilt {Carey und Hughes 1967;Chaudhuri 1970;Conway u. Mitarb. 1968;Khan u. Mitarb.…”

Section: Diskussion Häufigkeitunclassified

Die infektiöse Prothesen-Endokarditis Zur Problematik septischer Krankheitsbilder nach Verwendung alloplastischer Prothesen in der Kardiochirurgie*

Sadony¹

1972

Thorac cardiovasc Surg

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“…Since numerous blood cultures were sterile, diagnosis and treatment were delayed. Early surgical reintervention is necessary for eradication of fungal cardiac infections after valve operation [7,16]. When fungal endocarditis had been diagnosed in our patient, amphotericin B was started immediately and he underwent reoperation 72 h later.…”

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confidence: 99%