Furan as a Building Block in Synthesis

The Rearrangement of tert-Butylperoxides for the Construction of Polysubstituted Furans

“…Furan as an important class of five-membered heterocycles can be found in many natural compounds, pharmaceuticals, and biochemicals. Polysubstituted furans play an important role in organic chemistry due to not only their wide occurrence as key structural units in many natural products but also their usefulness as building blocks in synthetic chemistry . For these reasons, the exploration of new methods for the synthesis of polysubstituted furans continues to attract the interest of chemists .…”

Visible-Light Induced Direct Synthesis of Polysubstituted Furans from Cyclopropyl Ketones

“…As one of the most important heterocycles, furan derivatives have exhibited versatile applications in organic synthesis as synthetic intermediates and in the chemical industry to afford commercial products such as pharmaceuticals, pesticides, and functional polymers . Therefore, efficient synthesis of furans, especially in atom-economical pathways, has attracted considerable attention from the realm of organic synthesis .…”

Solvent-Free DABCO-Mediated [3 + 2] Cycloadditions of Donor–Acceptor Cyclopropanes with Aldehydes: Strategy for Synthesis of Fully Substituted Furans

“…Furans are an important class of five-membered heterocycles because of their diverse and potent biological properties in many pharmaceutical and natural products . Polysubstituted furans have also frequently been employed as basic building blocks in synthetic chemistry and as great potential skeletons in materials science . Typical methods for the synthesis of furans deal with the approaches based on both the Feist–Bénary cyclocondensation and the Paal–Knorr cyclocondensation .…”