2019
DOI: 10.3390/pharmaceutics11060277
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Fused Deposition Modeling 3D Printing: Test Platforms for Evaluating Post-Fabrication Chemical Modifications and In-Vitro Biological Properties

Abstract: 3D printing is attracting considerable interest for its capacity to produce prototypes and small production runs rapidly. Fused deposit modeling (FDM) was used to produce polyvalent test plates for investigation of the physical, chemical, and in-vitro biological properties of printed materials. The polyvalent test plates (PVTPs) are poly-lactic acid cylinders, 14 mm in diameter and 3 mm in height. The polymer ester backbone was surface modified by a series of ramified and linear oligoamines to increase its hyd… Show more

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Cited by 18 publications
(15 citation statements)
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“…Moreover, the 3D printed plates showed an antifungal activity against Candida albicans. This work put the basis for further studies in the chemical functionalization of 3D printed materials [6].…”
Section: Fused Deposition Modelling (Fdm)mentioning
confidence: 90%
“…Moreover, the 3D printed plates showed an antifungal activity against Candida albicans. This work put the basis for further studies in the chemical functionalization of 3D printed materials [6].…”
Section: Fused Deposition Modelling (Fdm)mentioning
confidence: 90%
“…PLA sterilization can be done with hydrogen peroxide, ethylene oxide, gamma irradiation, and electron beam with minimal change in its mechanical properties [47]. Additionally, postprocessing techniques, such as iodine coating and side chain modification for hydrophilicity, can further enhance antibacterial properties [48].…”
Section: D-filamentsmentioning
confidence: 99%
“…PLA sterilization can be done with hydrogen peroxide, ethylene oxide, gamma irradiation, and electron beam with minimal change in its mechanical properties [ 47 ]. Additionally, postprocessing techniques, such as iodine coating and side chain modification for hydrophilicity, can further enhance antibacterial properties [ 48 ]. Although PLA has promising potential, its use for direct body contact has not been approved by ISO 10993 because of its incompatibility with high temperature sterilization techniques [ 49 ].…”
Section: D-filamentsmentioning
confidence: 99%
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“…(47) Additionally, postprocessing techniques, such as iodine coating and side chain modi cation for hydrophilicity, can further enhance antibacterial properties. (48) Although PLA has promising potential, its use for direct body contact has not been approved by ISO 10993 because of its incompatibility with high temperature sterilization techniques. (49) However, alternative sterilization options exist, and PLA's non-cytotoxic and biodegradable qualities make it desirable for use during the COVID-19 pandemic.…”
Section: D-filamentsmentioning
confidence: 99%