2019
DOI: 10.1016/j.biopha.2019.108988
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Fusobacterium nucleatum, the communication with colorectal cancer

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Cited by 29 publications
(15 citation statements)
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References 87 publications
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“…Therefore, MPE research can contribute to the establishment of causality 106,142 . Recently, the concept of MPE has been increasingly recognized in the literature [143][144][145][146][147][148][149][150][151][152] . While somewhat overlapping with the concepts of "molecular epidemiology" and "systems epidemiology", MPE places particular emphasis on tumor tissue analyses for better pathobiological understanding.…”
Section: Transdisciplinary Epidemiologymentioning
confidence: 99%
“…Therefore, MPE research can contribute to the establishment of causality 106,142 . Recently, the concept of MPE has been increasingly recognized in the literature [143][144][145][146][147][148][149][150][151][152] . While somewhat overlapping with the concepts of "molecular epidemiology" and "systems epidemiology", MPE places particular emphasis on tumor tissue analyses for better pathobiological understanding.…”
Section: Transdisciplinary Epidemiologymentioning
confidence: 99%
“…Importantly, secreted serine protease fusolisin degrades extracellular matrix proteins as well as cleaves the most abundant immunoglobulin at the mucosal surface (IgA), contributing to the inactivation of the host defense and disease progression ( Bachrach et al, 2004 ; Doron et al, 2014 ). To add insult to injury, observed tissue environment modulation can give rise to other pathological conditions, such as colorectal cancer ( Luo et al, 2019 ).…”
Section: Pathogen-specific Effects On Neutrophil Functionsmentioning
confidence: 99%
“…Some novel findings have determined the roles of bacteria in CRC. Fusobacterium nucleatum was found to be enriched in both stools and tumor tissues of CRC patients, and promotes the tumorigenesis and chemoresistance of CRC (Luo et al, 2019). Peptostreptococcus anaerobius was reported as a promotor in colorectal carcinogenesis by modulating tumor immunity (Long et al, 2019).…”
Section: Introductionmentioning
confidence: 99%