FUT8 upregulates CD36 and its core fucosylation to accelerate pericyte-myofibroblast transition through the mitochondrial-dependent apoptosis pathway during AKI-CKD
Yaxi Shang,
Ziran Wang,
Fan Yang
et al.
Abstract:Background
Activation of pericytes leads to renal interstitial fibrosis, but the regulatory mechanism of pericytes in the progression from AKI to CKD remains poorly understood. CD36 activation plays a role in the progression of CKD. However, the significance of CD36 during AKI-CKD, especially in pericyte, remains to be fully defined.
Methods
GEO and DISCO database were used to analyze the expression of CD36 in pericyte during AKI-CKD; IRI to conduc… Show more
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