G0S2 Gene Polymorphism and Its Relationship with Carcass Traits in Chicken

Abstract

Gene single nucleotide polymorphisms can be used as auxiliary markers in molecular breeding and are an effective method to improve production performance. G0S2 is a key gene involved in regulating fat metabolism, but little research has been conducted on this gene regarding its role in poultry. In this study, the specialized commercial partridge chicken strain G0S2 gene was cloned and sequenced, and the relationship between the SNP sites on G0S2 and the carcass traits of chickens was investigated. The results showed that a total of seven SNPs were detected on G0S2 (g.102G > A, g.255G > A, g.349C > T, g.384A > G, g.386G > A, g.444G > A, g.556G > A). Two sites are located in the coding region and five sites are located in the 3′-UTR. SNPs located in the coding region are synonymous mutations. g.444G > A has a significant correlation with abdominal fat weight. The chickens with AG and GG genotypes have the highest abdominal fat weight, while the AA genotype is lower. The g.102G > A genotype has a significant correlation with live and abdominal fat weight. The live weight and abdominal fat weight of the chickens with AA and AG genotypes are at a higher level and have a larger gap than the GG genotype. Chickens with the AA genotype in g.556G > A had the lowest fat weight. The results of present study can provide practical information for molecular marker-assisted breeding of chicken carcass traits.

Polymorphisms of CRELD1 and DNAJC30 and their relationship with chicken carcass traits

“…Promoting muscle development and reducing fat deposition are the top priority in chicken breeding ( Guo et al, 2019 ). Therefore, many studies have been devoted to exploring the potential candidate genes, regulatory network, and molecular mechanism to improve chicken carcass traits ( Li et al, 2015 ; Allais et al, 2019 ; Fu et al, 2020 ; Zhang et al, 2020 ; Wang et al, 2021 ; Li et al, 2022 ; Yang et al, 2022 ). However, it still needs further research to unravel the underlying mechanisms of chicken carcass traits.…”

Exploring the Impact of Insertion/Deletion in FTO and PLIN1 Genes on Morphometric Traits in Sheep

“…Wu et al [24] conducted InDel detection and association analysis in seven Chinese sheep breeds, revealing a significant association between GHR-InDel and growth traits (p < 0.05). Yang et al [25] found significant associations between seven SNPs (g.102G > A, g.255G > A, g.349C > T, g.384A > G, g.386G > A, g.444G > A, g.556G > A) of G0S2 and carcass traits in chickens. Specifically, individuals with the AG genotype at g.444G > A exhibited the highest breast muscle weight, while individuals with the AA genotype at g.556G > A showed the lowest fat weight (p < 0.05).…”

LncEDCH1 g.1703613 T>C regulates chicken carcass traits by targeting miR-196-2-3p

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