G2B reviews: Epigenetics, epitranscriptomics, microRNAs and more: Emerging approaches to the study of genes, brain and behavior

Holmes, Allyson

doi:10.1111/gbb.12453

Genes Brain and Behavior

2018

DOI: 10.1111/gbb.12453

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G2B reviews: Epigenetics, epitranscriptomics, microRNAs and more: Emerging approaches to the study of genes, brain and behavior

Allyson Holmes

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“…Some microRNA molecules are capable of modifying histones and methylation of DNA, i.e. changes at the epigenetic level[26][27][28][29], which can eventually lead to the formation of pathology process. MicroRNA also affects many physiological and pathological processes in mammalian organisms.…”

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The role of microRNAs in animal physiology and pathology

Szczepanek

Pareek

Tretyn

2018

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MicroRNAs are a class of small, evolutionarily conserved, endogenous RNAs, capable of controlling gene expression. MicroRNAs are transcribed by RNA polymerases II and III, generating precursors that undergo a series of cleavage events to form mature microRNA. They play an important regulatory role in animals at the posttranscriptional levels by targeting mRNAs for direct cleavage of mRNAs or repression of mRNA translation. The main biological function of miRNA is the post-translation regulation of cells, like: proliferation and differentiation, cell death, fat metabolism, neuronal patterning and angiogenesis. These molecules are the main regulators of biological features of economic

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confidence: 99%

The role of microRNAs in animal physiology and pathology

Szczepanek

Pareek

Tretyn

2018

TRVS

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Overview of trends in global epigenetic research (2009–2017)

2019

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G2B reviews: Epigenetics, epitranscriptomics, microRNAs and more: Emerging approaches to the study of genes, brain and behavior

Cited by 2 publications

References 20 publications

The role of microRNAs in animal physiology and pathology

The role of microRNAs in animal physiology and pathology

Overview of trends in global epigenetic research (2009–2017)

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