Untitled

Abstract

The study explores the specifics of local involvement of structures of musculoskeletal apparatus in dysplastic process. The researchers estimated the significance of external and visceral phenotypic features for further development of pathologic process in children with joint hypermobility as one of the main manifestations of undifferentiated connective tissue dysplasia. It is established that the examined cohort have physiologic joint mobility as well as mild, medium or severe degree of joint hypermobility. The research of prognostic significance of correlation patterns of certain features of joint hypermobility in children enabled constructing conceptual contextual and abstracted mathematical model. It is established that most indicators of physical development are significant factors of phenotypic manifestation of joint hypermobility in children aged 4-6, but the most dominant are: body length, chest circumference, body mass, foot length and arm span. While the influence of such factors as platypodia, hand length, postural kyphosis and scoliosis is less significant compared to that of the indicators mentioned above.