2013
DOI: 10.17925/ohr.2013.09.2.102
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Gallbladder Cancer—Current Management Options

Abstract: Abstractcarcinoma of the gallbladder is an aggressive disease, often with a poor prognosis. although the incidence has remained relatively stable over the past decade, an increase in laparoscopic cholecystectomy has resulted in a increase in cases detected at earlier stages offering an opportunity for better prognosis. diagnostic techniques including ultrasound (uS), endoscopic uS (EuS), computed tomography (cT) with multiplanar reconstruction, magnetic resonance imaging (MRi), positron emission tomography (PE… Show more

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Cited by 3 publications
(4 citation statements)
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“…In addition to this, gallbladder carcinoma is not sensitive to radiotherapy and chemotherapy. All of these characteristics make gallbladder carcinoma as a highly lethal tumor with a five-year survival rate of less than 5% [16,21]. Many of the signs and symptoms of gallbladder carcinoma are nonspecific, so it is more likely to be diagnosed at an advanced stage in patients and is associated with a high mortality rate.…”
Section: Gallbladder Carcinomamentioning
confidence: 99%
See 1 more Smart Citation
“…In addition to this, gallbladder carcinoma is not sensitive to radiotherapy and chemotherapy. All of these characteristics make gallbladder carcinoma as a highly lethal tumor with a five-year survival rate of less than 5% [16,21]. Many of the signs and symptoms of gallbladder carcinoma are nonspecific, so it is more likely to be diagnosed at an advanced stage in patients and is associated with a high mortality rate.…”
Section: Gallbladder Carcinomamentioning
confidence: 99%
“…Moreover, diagnostic accuracy of EUS has been shown for T-stage: Tis-stage 100%, T1-stage 75.6%, T2-stage 85.3%, and T3,4-stage 92.7%. EUS also adds the possibility of fine needle aspiration (FNA) for tissue diagnosis of the primary as well as lymph nodes, where diagnostic accuracy approaches 100% [16,21].…”
Section: Gallbladder Carcinomamentioning
confidence: 99%
“…Gallbladder cancer (GBC) is the most common malignancy of the biliary tract and the fifth cancer of the gastrointestinal tract that is frequently diagnosed at an advanced stage due to non specific symptoms, anatomic location and aggressive biologic behavior, with a poor prognosis and 5-year survival rate of 5 to 15% [1][2][3][4]. GBC is characterized by local invasion, extensive regional lymph node metastasis, vascular encasement and distant metastases, mode of spread are direct, lymphatic, vascular, neural, intraperitoneal and intraductal [5].…”
Section: Introductionmentioning
confidence: 99%
“…Rizikovými fak tory jsou velikost konkrementu, délka tr vání cholecystolitiázy a recidivující cho lecystitidy. Všechny tyto faktory mohou vyvolat dysplastické a následně maligní změny v mukóze, i když dle dostupných studií je vývoj do karcinomu multifak toriální a přítomnost lithiázy je pouze jeden z faktorů [8].…”
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