Objective: To compare the outcomes of ultrasonic vessel sealing device and conventional method during laparoscopic cholecystectomy.Methodology: This prospective comparative study was carried at the Department of General Surgery, LUMHS during16-06-2021 to 25-01-2022. A total of 140 Patients with symptomatic gallstones assigned in two groups on surgeon’s pref-erence after fulfilling inclusion criteria for LC. Group A, LC done by Using clips & cautery method and group B, LC done by using harmonic scalpel. All surgeries was performed by senior consultant. Data was collected via pre-structured proforma. The outcomes was measured.Results: Mean duration of procedure difference was significantly less in patients with LC was done with harmonic scal-pel in comparison with conventional method [Mean difference -6.71±1.24 min; p=0.0005]. Rate of intraoperative bleed-ing more than 100 ml was significant [A=35.7% vs. B=0; p=0.0005]. Similarly rate of postoperative bleeding was signifi-cant [A=17.14% vs. B=5.71%; p=0.034]. Rate of gallbladder perforation and lateral tissue damage was also significant [14.3% vs. 40%; p=0.001] and [0% vs. 10%; =0.013] respectively. Drain content was significant [A=72.3% vs. B=11.4%; p=0.0005]. Hospital stay more than 1 day was significantly less in patients [A=62.8% vs. B=30% p=0.0005].Conclusion:The ultrasonic vascular sealing device achieves satisfactory hemobiliary stasis in most of patients and may serve as a safer substitute to definitive cystic duct and artery clipping.
Key words: laparoscopic cholecystectomy, conventional method, ultrasonic vessel sealing device, outcomes.