Gallbladder wall thickening associated with infectious mononucleosis

Yoshie, Koichiro; Ohta, Mai; Okabe, Nobuhiko; Komatsu, Takashi; Umemura, Satoshi

doi:10.1007/s00261-004-0173-8

Cited by 16 publications

(9 citation statements)

References 6 publications

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“…Normally, GBW appears as a pencil-thin echogenic line at US examination. In our case, abdominal US showed a GBW thickness that greatly exceeded 3 mm, the upper limit of normal range in fasting subjects [2]. Diffuse gallbladder thickening may produce a diagnostic problem; the finding itself is unspecific and may result from a broad spectrum of pathological conditions, intrinsic as well as extrinsic to the biliary tract [4].…”

Section: Discussionmentioning

confidence: 98%

“…Only a few cases of GBWT (gall bladder wall thickening) or intrathoracic inflammatory pseudotumor in patients with IM are described in the literature, especially in immunocompetent adolescent patients [2,3]. Normally, GBW appears as a pencil-thin echogenic line at US examination.…”

Section: Discussionmentioning

confidence: 99%

“…Diffuse gallbladder thickening may produce a diagnostic problem; the finding itself is unspecific and may result from a broad spectrum of pathological conditions, intrinsic as well as extrinsic to the biliary tract [4]. When associated with serologic evidence of primary EBV-infection, the finding of GBWT and enlarged nodes at the porta hepatis allows exclusion of other conditions [2].…”

Section: Discussionmentioning

confidence: 99%

“…Nonetheless, a wide variety of atypical presentations with complications affecting multiple organ systems during acute IM, is described in the literature [1,2] with an increase in the number of teenagers who are susceptible to a severe case of the disease. The great variability of the clinical picture makes the diagnosis difficult and questionable: serological outcome is gold standard, but the radiological spectrum is useful when symptoms persist or are unusually prominent.…”

Section: Introductionmentioning

confidence: 99%

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Imaging spectrum of EBV-infection in a young patient

Pelliccia

Sereno

Cecamore

et al. 2008

Journal of Ultrasound

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A wide variety of atypical presentations with complications affecting multiple organ systems during acute infectious mononucleosis (IM) is described in the literature, with an increase in the number of teenagers who are susceptible to a severe case of the disease. We report a case of a 14-year-old girl with severe IM and acute abdominal pain. Ultrasonographic (US) evaluation showed a marked thickening of the gallbladder wall (GBW) with enlargement of some mesenteric lymph nodes. CT scan showed multiple enlarged lung nodules of various sizes and a small pleural and pericardial effusion; a hypodense solid mass of unknown etiology was detected in the anterior mediastinum, mimicking a malignant tumor. Hematological analysis of peripheral blood smear was performed to exclude neoplastic pathology. IM was identified as the only underlying disease. The patient was carefully monitored: clinical evaluation, laboratory analysis and US examination were repeated at weekly intervals, until recovery.Sommario Gli adolescenti possono talvolta presentare forme aggressive di mononucleosi infettiva (MI), che si manifestano con quadri atipici e aspecifici e si accompagnano a complicanze di diversa gravità a carico di vari organi e apparati. Riportiamo il caso di una ragazza di 14 anni, giunta alla nostra osservazione per un quadro di mononucleosi infettiva (MI) e dolore addominale acuto; le indagini diagnostiche evidenziavano all'ecografia addominale la presenza di ispessimento della parete colecistica (>3 mm) con versamento pericolecistico e di linfonodi ingranditi all'ilo epatico; alla TC veniva confermato il quadro ecografico addominale e si evidenziava inoltre una massa solida ipodensa a livello del mediastino anteriore, con versamento pleurico e pericardico e presenza di numerosi linfonodi mediastinici ingranditi. Data la gravità del quadro, è stato necessario escludere patologie neoplastiche. La paziente è stata attentamente monitorizzata durante la degenza, ed ha presentato una completa, ma lenta risoluzione dei sintomi. ª

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Imaging spectrum of EBV-infection in a young patient

Pelliccia

Sereno

Cecamore

et al. 2008

Journal of Ultrasound

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“…Ultrasonografik görüntülemede safra kesesi duvar kalınlıkları 4,2-19 mm arası bildirilmiştir. Bu hastaların genel özellikleri Tablo I'de özetlenmiştir (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18). Hastamız da bu komplikasyonun nadir görüldüğü yaş grubundaydı.…”

Section: Discussionunclassified

A Rare Comlication of Ebstein-Barr Virus Infection: Acalculous Cholecystitis

Ocak¹,

Akçaboy²,

Çakmakçı³

et al. 2016

jpr

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GirişErken çocukluk döneminde Ebstein-Barr virüs (EBV) enfeksiyonu genellikle subklinik veya viral üst solunum yolu enfeksiyonunu taklit eden belirtilerle seyreder. Ancak geç çocukluk ve adölesan döneminde ateş, tonsillit ve lenf bezlerinde şişlikle karakterize enfeksiyöz mononükleoz klinik tablosuna yol açabilir. EBV kendi kendini sınırlayan bir enfeksiyon olmakla birlikte çok çeşitli komplikasyonlar bildirilmiştir. Hepatitle beraber hafif serum transaminaz yüksekliği sık görülen bulgu olsa da çocuklarda EBV ilişkili akut akalkülöz kolesistit (AAK) nadiren bildirilmiştir (1). Burada EBV enfeksiyonu sırasında gelişen ve seyrinde sorunsuz iyileşen bir akalkülöz kolesistit olgusu sunulmuştur. Olgu Sunumuİki yaşında erkek hasta iki gündür devam eden ateş, göz çevresinde ve karında şişlik şikayetleri ile başvurdu. Özgeçmiş ve soy geçmişinde özellik yoktu. Fizik incelemesinde genel ÖzABS TRACT Ebstein-Barr virüs (EBV) enfeksiyonu adölesan dönemde ateş, tonsillit, lenfadenit şeklinde seyreden enfeksiyöz mononükleoz tablosuna yol açsa da erken çocukluk döneminde enfeksiyon genellikle subklinik seyreder. EBV enfeksiyonu sırasında karaciğer enzim yüksekliği alışılmış bir bulgudur ancak akut akalkülöz kolesistit (AAK) nadir görülür. Burada akut EBV enfeksiyonu seyrinde gelişen AAK olgusu sunulmuştur. Hekimler EBV'ye bağlı gelişen enfeksiyoz mononükleoz seyri sırasında akut kolesistit gelişebileceğini, klinik iyileşmeye paralel olarak bu komplikasyonun düzeleceğini akılda bulundurmalıdır. Anahtar Kelimeler: Akut akalkülöz kolesistit, Ebstein-Bar virüs, çocuk Infection with Ebstein-Barr virüs (EBV) causes clinical signs such as fever, tonsillitis, lymphadenitis in adolescents, whereas it is mainly asymptomatic during early childhood. Elevations in liver function tests are known signs in EBV infection but acute acalculous cholecystitis (AAC) is rare. Herein, we report AAC in the course of acute EBV infection. Physicians should keep in mind that acute cholecystitis may develop during the course of EBV related infectious mononucleosis and this complication will recover-paralel to the clinical improvement of the primary disease.

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Mononucleosis

2015

Diagnostic Imaging: Gastrointestinal

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Gallbladder wall thickening associated with infectious mononucleosis

Cited by 16 publications

References 6 publications

Imaging spectrum of EBV-infection in a young patient

Imaging spectrum of EBV-infection in a young patient

A Rare Comlication of Ebstein-Barr Virus Infection: Acalculous Cholecystitis

Mononucleosis

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