GALNT6 promotes bladder cancer malignancy and immune escape by epithelial-mesenchymal transition and CD8+T cells
Xiaoxin Sun,
Haotian Wu,
ABDULLAH AL-DANAKH
et al.
Abstract:Bladder cancer (BC) ranks as the fourth cancer in males and the tenth most common cancer worldwide. Conventional treatment modalities, including surgery, radiation, chemotherapy, and immunotherapy, have limited efficacy in certain advanced instances. The involvement of GALNT6-mediated aberrant O-glycosylation modification in several malignancies and immune evasion is a subject of speculation. However, its significance in BC has not been investigated. Through the integration of bioinformatics analysis and labor… Show more
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