Gamma Splines and Wavelets

Olkkonen, H.; Olkkonen, Juuso

doi:10.1155/2013/625364

Cited by 2 publications

(2 citation statements)

References 13 publications

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“…As ligands of sterol regulated transcription factors, oxysterols control gene expression in lipid metabolism, regulate immune and inflammatory responses, and modify cellular calcium signaling by acting at transcriptional, translational-and post-translational level. A number of key proteins implicated in the control of metabolic homeostasis are recognized targets of oxysterol signaling [85][86][87][88][89]. Of note, by acting as a "sink" to safely store harmful cholesterol metabolites, AT plays a key role in regulating the trafficking of oxysterols and peroxidation by-products, action that appears beneficial for preserving glucose homeostasis [90][91][92].…”

Section: Oxidative Stress and Cellular Senescence: Novel Actors In Th...mentioning

confidence: 99%

Adipose Tissue Plasticity in Response to Pathophysiological Cues: A Connecting Link between Obesity and Its Associated Comorbidities

Fano¹,

Bartolini²,

Tortoioli³

et al. 2022

Preprint

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Adipose tissue (AT) is a remarkably plastic and active organ with functional pleiot-ropism and high remodeling capacity. Although the expansion of fat mass, by defini-tion, represents the hallmark of obesity, the dysregulation of the adipose organ emerges as the forefront of the link between adiposity and its associated metabolic and cardio-vascular complications. The dysfunctional fat displays distinct biological signatures, which include enlarged fat cells (i.e., adipocyte hypertrophy), low-grade inflammation, impaired redox homeostasis, and cellular senescence. While these events are orches-trated in a cell-type, context-dependent and temporal manner, the failure of the adipose precursor cells to form new mature adipocytes appears the main instigator of the adi-pose dysregulation, which, ultimately, poses a deleterious milieu either by promoting ectopic lipid overspill in non-adipose targets (i.e., lipotoxicity) or by inducing an al-tered secretion of different adipose-derived hormones (i.e., adipokines and lipokines). This novel paradigm (“expandability hypothesis”) challenges and extends previous “adipocentric view”, which implies a reduced plasticity of the adipose organ at the nexus between “unhealthy” fat expansion and the development of obesity-associated comorbidities. In this review, we will briefly summarize the potential mechanisms by which adaptive changes to variations of energy balance may impair adipose plasticity and promote fat organ dysfunction. We will also highlight the conundrum with the perturbation of the adipose microenvironment and the development of cardio-metabolic complications by focusing on adipose lipoxidation and cellular senescence. Finally, we discuss the sci-entific rationale for proposing adipose organ plasticity as a target to curb/prevent adi-posity-linked cardio-metabolic complications.

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Section: Oxidative Stress and Cellular Senescence: Novel Actors In Th...mentioning

confidence: 99%

Adipose Tissue Plasticity in Response to Pathophysiological Cues: A Connecting Link between Obesity and Its Associated Comorbidities

Fano¹,

Bartolini²,

Tortoioli³

et al. 2022

Preprint

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“…During the war, the Finnish schlager gained official approval as part of the entertainment to boost morale at the front. 136 The proportion of annual recordings of dance music grew rapidly in the early 1930s. It first amounted to some 50 per cent, but from 1932 onwards to over 90 per cent.…”

mentioning

confidence: 99%

“They Played it on Saturday Nights in a Barn.” Gramophone Practices and Self-Made Modernity in Finland from the 1920s to the 1940s

Männistö-Funk

2013

HCM

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This article studies rural gramophone use in Finland from the 1920s to the 1940s, based on source material of written memories related to the long Nordic tradition of folklore surveys. The characteristic rurality of the Finnish pre-war and war-time society offers an opportunity to study the non-urban appropriation of modern technology and to approach rural modernity as locally produced on the one hand, but crucial to the societal and cultural modernisation processes on the other. The article uses a practice theoretical approach and argues for an understanding of grass-root modernity as a dynamic system of practices combining old and new elements. By scrutinising the material elements, meanings and competencies linked together in rural gramophone practices, the article describes and analyses diverse forms of rural activity and innovativeness around the gramophone, peaking in the popular phenomenon of secret dances during the Second World War.

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Gamma Splines and Wavelets

Cited by 2 publications

References 13 publications

Adipose Tissue Plasticity in Response to Pathophysiological Cues: A Connecting Link between Obesity and Its Associated Comorbidities

Adipose Tissue Plasticity in Response to Pathophysiological Cues: A Connecting Link between Obesity and Its Associated Comorbidities

“They Played it on Saturday Nights in a Barn.” Gramophone Practices and Self-Made Modernity in Finland from the 1920s to the 1940s

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