Gastroduodenal ulceration in foals

Murray, M. J.

doi:10.1111/j.2042-3292.1999.tb00948.x

Cited by 34 publications

(34 citation statements)

References 41 publications

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“…In the majority of horses from our monitored group, the lesions of squamous mucosa were localised near the margo plicatus at the smaller curvature, but in 37% of the horses the mucosa surrounding the margo plicatus was affected along its whole length. In more severe cases, the lesions had also spread to the squamous mucosa of the saccus caecus (Murray et al, 1998), which can also be confirmed by our experience.…”

Section: Discussionsupporting

confidence: 77%

“…The margo plicatus is a predilection site for ulcers occurring in the squamous mucosa Murray, 1998). In the group with gastric lesions in the squamous mucosa, all horses had ulcers localised near the margo plicatus.…”

Section: Discussionmentioning

confidence: 99%

“…The ulcers are primarily located in the squamous mucosa along the lesser and greater curvatures near the margo plicatus, or they occur in the glandular mucosa and duodenum. In mature horses gastric ulceration occurs primarily along the margo plicatus (Hammond et al, 1986;Murray et al, 1989;Murray, 1998). Several pathomorphological studies have been performed on the localisation of EGUS.…”

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confidence: 99%

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Pathomorphological study on gastroduodenal ulceration in horses: Localisation of lesions

Bezděková

Jahn

Vyskočil

2007

Acta Veterinaria Hungarica

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Gastroduodenal ulceration is a prevalent disease in foals and adult horses. Decreased performance as well as fatal complications relate to this syndrome. The objective of our study was to determine the prevalence of gastric ulceration in a mixed population of horses by postmortem examination and to evaluate a possible association between equine gastric ulcer syndrome (EGUS) and sex or age of the examined horses, to evaluate the localisation of lesions in the proximal part of the gastrointestinal tract and to determine the occurrence of gastric parasites. Postmortem examinations were performed on 71 horses over a period of 24 months. Gastric ulcers were found in 52 horses (73.2%). There was no significant association between age or sex and occurrence of gastric ulcers. In all horses the squamous mucosa lesions were localised near the margo plicatus (100% of the cases), whereas in 23 horses the lesions were near the margo plicatus and lesser curvature and in 7 horses at the greater curvature. In 18 horses the mucosa was affected in the whole extent of the margo plicatus and in 1 horse diffuse lesions of the squamous mucosa were noted. Lesions of the glandular mucosa were localised in 11 horses at the fundic area, in 1 horse they occurred in the pylorus, and in 10 horses diffuse lesions of the glandular mucosa were recorded. A low prevalence of Gasterophilus intestinalis infection was detected (1 horse, 1.4%). We have confirmed that gastric ulcers are a common problem in horses and duodenal or oesophageal ulceration is rare (not a single case of the latter was found in this study). Lesions in the glandular mucosa of the stomach are more frequent in suckling foals than in older animals. Lesions of the glandular mucosa are also common in adult horses, and a complete gastroscopic examination including examination of the pylorus is advisable to evaluate this syndrome.

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Section: Discussionsupporting

confidence: 77%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Pathomorphological study on gastroduodenal ulceration in horses: Localisation of lesions

Bezděková

Jahn

Vyskočil

2007

Acta Veterinaria Hungarica

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“…Presumably, the non-secretory squamous portion of gastric mucosa predisposes to less effective protection and is more likely to develop lesions than the glandular portion. On the contrary, the gastric glandular mucosa which is responsible for complete gastric secretion of protective or aggressive substances is more resistant to ulceration (Murray 1997). Positive correlation between endurance exercise in racehorses and prevalence, or severity, of gastric ulcers was reported by Murray (1994) or Orsini and Pipers (1997).…”

Section: Discussionmentioning

confidence: 83%

Gastric Ulceration and Exercise Intensity in Standardbred Racehorses in Czech Republic

Bezděková¹,

Jahn²,

Vyskočil³

et al. 2005

Acta Vet. Brno

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Bezdûková, B., P. Jahn, M. Vyskoãil, J. Plach˘: Gastric Ulceration and Exercise Intensityin Standardbred Racehorses in Czech Republic. Acta Vet. Brno 2005, 74: 67-71.The objective of our study was to determine prevalence of equine gastric ulcer syndrome (EGUS) in individual groups of Standardbred horses in the Czech Republic divided in accordance to training intensity, to determine association between training intensity and prevalence of gastric ulcers and severity of gastric ulcers in these horses. Fifty four 2-year-old or older Standardbred racehorses engaged in routine training and racing were selected for this study. Prevalence of gastric ulcers was 20.00% in Standardbred racehorses with no training intensity, 16.67% in horses in mild training, 68.42% in horses in intermediate training and 79.12% in horses in high intensity training. Significant association was proven between training intensity and occurrence of gastric ulcers. Positive correlation between training intensity and gastric ulceration severity was proven as well.From the results we concluded that gastric ulcers are common in Standardbred horses in training in Czech Republic. Their prevalence and severity is dependent on the training intensity. Gastric ulcer, prevalence, training, standardbred, racehorse, Czech RepublicGastric ulceration in horses (equine gastric ulcer syndrome -EGUS) has aroused interest during the last decades due to new intravital diagnostic procedures and results of intensive study of ethiopathogenesis and therapy of this disease.In many studies, high prevalence of the disease in racehorses and horses in active race training was proven. The prevalence of EGUS ranges from 66% (Hammond et al.1986) to more than 90% (Murray 1994). Horses used for pleasure, riding lessons or show have lower prevalence (37%) and severity of gastric ulcers (Murray et al. 1989). Prevalence of EGUS in the Czech Republic is 62.96% (Bezdûková et al. 2004, parallel publication).It was proven that the prevalence and severity of gastric ulceration increases with the duration of race training or endurance training (Murray 1994;Orsini and Pipers 1997). This is consistent with pathomorphological findings in 195 Thoroughbred racehorses reported by Hammond et al. (1989). In this study, the prevalence of EGUS was higher in horses in active training and racing (80%) than in those that were not in training (37%), and similar results were reported by Murray et al. (1989). Association between occurrence of EGUS and training intensity has not been evaluated in Middle Europe yet.The cause of gastric ulcers is still unknown. Diet and feed management are considered potential risk factors. Lower prevalence and severity of gastric ulcers occur in horses which are kept on pasture with continuous feed intake than in those which are fed with high-grain diet. Administration of nonsteroidal anti-inflammatory drugs was reported as a cause of gastric ulceration in many species (MacAllister et al. 1993), however the occurrence of ulcers is high even in horses with no hist...

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“…Ruptures affected both the glandular and the non-glandular portions, and usually measured 20cm. Histologically, the structural and functional differences between the epithelia of the two mucosae influence the aspect of ulcerative lesions on the gastric wall (Murray 1999, Andrews et al 2006. However, no study has evaluated and compared the distension of the gastric wall in the glandular and the non-glandular portions.…”

Section: Discussionmentioning

confidence: 99%

Resistance to rupture of the equine stomach

et al. 2016

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RESUMO.-[Resistência à ruptura do estômago equino.]A cólica é um dos problemas mais comuns na clínica de equinos sendo responsável por grande número de mortes. A ruptura gástrica tem sido amplamente descrita na literatura e acomete número expressivo de animais. A dilatação gástrica, que antecede a ruptura, pode advir do consumo excessivo de capim recém-cortado, ingestão rápida de água, infestação por Gastherophilus, ocorrência de íleo paralítico e obstruções intestinais distais. A ruptura gástrica tem sido amplamente descrita na literatura e acomete um número expressivo de animais. Este estudo objetivou determinar a resistência à ruptura do estômago equino mediante a insuflação de ar atmosférico (mmHg) e do preenchimento com água (L). Foram utilizados 40 estômagos de equinos adultos jovens (20 machos castrados e 20 fêmeas) sem raça definida. Medidas relativas ao comprimento total do órgão (cm), peso do órgão (g), curvatura maior (cm), curvatura menor (cm) e altura (cm) foram aferidas e não diferiram entre machos e fêmeas (p>0,05). No entanto, os estômagos dos machos apresentaram medidas superiores as das fêmeas e por assim serem, comportaram um maior volume de água (p<0,05). No teste de resistência mediante insuflação de ar atmosférico não houve diferença entre machos e fêmeas (93mmHg). Os rompimentos ocorreram ao longo da curvatura maior (99%) nas faces visceral (80%) e diafragmática (20%) e abrangeram todas as camadas da parede gástrica. Apesar de ser um órgão relativamente pequeno, o estômago dos equinos apresenta considerável resistência à ruptura, seja por líquido ou por ar atmosférico. Equine colic is an important and common cause of disease and death in horses. Gastric rupture has been extensively described in the literature, and is known to affect expressive numbers of horses. Gastric dilatation, which precedes rupture, may be observed when the animal consumes large amounts of recently harvested grass or drinks water too fast, though diagnosis criteria also include infestation with Gastherophilus and the presence of ileus and distal intestinal obstructions. The objective of the present study was to determine the resistance to rupture of the equine stomach to air (mm Hg) and water (L) injection. Forty stomachs of young horses (20 geldings and 20 mares) with no defined breed were analyzed. Total organ length (cm), weight (g), greater curved length (cm), lesser curved length (cm) and height (cm) were measured, with no statistical difference between males and females (p > .05). However, stomachs of horses were larger than those of mares and therefore presented higher volumetric capacity (p<0.05). No difference between males and females was observed in the pressure assay (93mmg Hg). Rupture occurred along the greater curvature (99%) and on the visceral (80%) and diaphragmatic (20%) surfaces, across all layers of the gastric wall. Although the equine stomach is relatively small, the organ is considerably resistant to rupture, whether by injection of air or liquid. Horses and mares exhibit similar resistance va...

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Gastroduodenal ulceration in foals

Cited by 34 publications

References 41 publications

Pathomorphological study on gastroduodenal ulceration in horses: Localisation of lesions

Pathomorphological study on gastroduodenal ulceration in horses: Localisation of lesions

Gastric Ulceration and Exercise Intensity in Standardbred Racehorses in Czech Republic

Resistance to rupture of the equine stomach

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