Gastrointestinal failure score alone and in combination with SOFA score in the assessment of the critically ill patients

Abed, N; Mohammed, L; Metwaly, Amna; Hussien, Mohammed Naseem

doi:10.1186/cc9929

Cited by 2 publications

(2 citation statements)

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“…One such tool is the acute GI injury (AGI) score which was proposed by the Working Group on Abdominal Problems of the European Society of Intensive Care Medicine (ESICM) [ 6 ]. There have been studies that have used the AGI score independently as well as in combination with the SOFA score to assess its influence on outcomes in critically ill patients [ 7 , 8 ]. Despite increasing evidence of its importance, surveys have shown that the monitoring of the GI system and measurement of IAP has been woefully inadequate across intensive care units (ICUs) in the West [ 9 , 10 ].…”

Section: Introductionmentioning

confidence: 99%

Acute Gastrointestinal Injury in Critically Ill Patients in a South Indian Intensive Care Unit: A Prospective, Observational, Preliminary Study

Taggarsi,

Sampath

2024

Cureus

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Section: Introductionmentioning

confidence: 99%

Acute Gastrointestinal Injury in Critically Ill Patients in a South Indian Intensive Care Unit: A Prospective, Observational, Preliminary Study

Taggarsi,

Sampath

2024

Cureus

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“…This study also noted that the mean GI failure score for the first 3 days of ICU admission had a high prognostic value for ICU mortality. A later study in two Egyptian ICUs [18], employing the same GI failure score, examined the predictive power of the SOFA score, GI failure and the combination of the two. It reached similarly positive results.…”

Section: Introductionmentioning

confidence: 99%

Improved ICU mortality prediction based on SOFA scores and gastrointestinal parameters

et al. 2019

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BackgroundThe Sequential Organ Failure Assessment (SOFA) score is commonly used in ICUs around the world, designed to assess the severity of the patient's clinical state based on function/dysfunction of six major organ systems. The goal of this work is to build a computational model to predict mortality based on a series of SOFA scores. In addition, we examined the possibility of improving the prediction by incorporating a new component designed to measure the performance of the gastrointestinal system, added to the other six components.MethodsIn this retrospective study, we used patients’ three latest SOFA scores recorded during an individual ICU stay as input to different machine learning models and ensemble learning models. We added three validated parameters representing gastrointestinal failure. Among others, we used classification models such as Support Vector Machines (SVMs), Neural Networks, Logistic Regression and a penalty function used to increase model robustness in regard to certain extreme cases, which may be found in ICU population. We used the Area under Curve (AUC) performance metric to examine performance.ResultsWe found an ensemble model of linear and logistic regression achieves a higher AUC compared related works in past years. After incorporating the gastrointestinal failure score along with the penalty function, our best performing ensemble model resulted in an additional improvement in terms of AUC metrics. We implemented and compared 36 different models that were built using both the information from the SOFA score as well as that of the gastrointestinal system. All compared models have approximately similar and relatively large AUC (between 0.8645 and 0.9146) with the best results are achieved by incorporating the gastrointestinal parameters into the prediction models.ConclusionsOur findings indicate that gastrointestinal parameters carry significant information as a mortality predictor in addition to the conventional SOFA score. This information improves the predictive power of machine learning models by extending the SOFA to include information related to gastrointestinal organ system. The described method improves mortality prediction by considering the dynamics of the extended SOFA score. Although tested on a limited data set, the results' stability across different models suggests robustness in real-time use.

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Gastrointestinal failure score alone and in combination with SOFA score in the assessment of the critically ill patients

Cited by 2 publications

References 2 publications

Acute Gastrointestinal Injury in Critically Ill Patients in a South Indian Intensive Care Unit: A Prospective, Observational, Preliminary Study

Acute Gastrointestinal Injury in Critically Ill Patients in a South Indian Intensive Care Unit: A Prospective, Observational, Preliminary Study

Improved ICU mortality prediction based on SOFA scores and gastrointestinal parameters

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