2011
DOI: 10.1016/j.jep.2011.03.002
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Gastroprotective and ulcer healing effects of essential oil from Hyptis spicigera Lam. (Lamiaceae)

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Cited by 53 publications
(52 citation statements)
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“…A healing activity was produced with 87% reduction in ulcerative lesion area. It increased COX-2 (75%) and EGF (115%) expression in gastric mucosa so increase the healing of acetic acid-induced gastric lesions (Takayama et al 2011). a-Terpineol exhibited gastroprotective activity against ethanol-induced ulcers.…”
Section: Discussionmentioning
confidence: 99%
“…A healing activity was produced with 87% reduction in ulcerative lesion area. It increased COX-2 (75%) and EGF (115%) expression in gastric mucosa so increase the healing of acetic acid-induced gastric lesions (Takayama et al 2011). a-Terpineol exhibited gastroprotective activity against ethanol-induced ulcers.…”
Section: Discussionmentioning
confidence: 99%
“…However, this yield was different in other regions, as in three different locations at Sidi Feradj, Djelfa and Saïda in Algeria, whose oils hydrodistillation yields were 0.5 , 0.8 and 0.9 56 , respectively. Moreover, the terpenic compounds of P. halepensis have bactericidal, fungicidal, insecticidal, anticarcinogenic, pesticidal, antioxidant, analgesic and sedative effects 57 . Therefore, our results showed that EOP exhibited an excellent protective effect and may be considered as a useful source of cellular defense agent in liver and kidney tissues against aspirin.…”
Section: Discussionmentioning
confidence: 99%
“…The family has a cosmopolitan distribution and contains many plant species with culinary and medicinal purposes; examples of the former are basil, mint, rosemary, sage, savory, marjoram, oregano, thyme, lavender, and perilla (Naghibi et al, 2005). The Lamiaceae family of plants have been used since ancient times as folk remedies for various health problems such as common cold, throat infections, acaricidal, psoriasis, seborrheic eczema, hemorrhage, menstrual disorders, miscarriage, ulcer, spasm and stomach problems (Takayama et al, 2011;Loizzo et al, 2010;. Ribeiro et al, 2010).…”
mentioning
confidence: 99%